Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.54 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.54 |
| ▸ | PARP1 | P09874 | 19/20 | 0.54 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3577370 | 0.91 | KDR (0.65) | KDRAURKBPARP1DHODH | |
| SCHEMBL6582952 | 0.88 | KDR (0.41) | KDRAURKBPARP1 | |
| SCHEMBL3586255 | 0.86 | KDR (0.41) | KDRAURKBPARP1 | |
| SCHEMBL3580135 | 0.85 | AURKB (0.61) | KDRAURKBPARP1DHODH | |
| SCHEMBL3577208 | 0.84 | PARP1 (0.55) | AURKBPARP1DHODH | |
| SCHEMBL6580677 | 0.79 | KDR (0.49) | KDRAURKBPARP1DHODH | |
| SCHEMBL13225614 | 0.79 | PARP1 (0.62) | KDRAURKBPARP1DHODH | |
| SCHEMBL3582780 | 0.78 | AURKB (0.49) | KDRAURKBPARP1DHODH | |
| SCHEMBL3576435 | 0.77 | PARP1 (0.58) | KDRAURKBPARP1DHODH | |
| SCHEMBL3582141 | 0.75 | AURKB (0.75) | KDRAURKBPARP1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7781596-B1 | Substituted 2-phenylbenzimidazoles, the production thereof and their use | ABBOTT LABORATORIES (US) | 2010-08-24 | — | — | US | disclosed |
| US-7781596-B1 | Substituted 2-phenylbenzimidazoles, the production thereof and their use | ABBOTT LABORATORIES (US) | 2010-08-24 | — | — | US | disclosed |