Phenolsulphonic Acid

Phenolsulphonic Acid

SCHEMBL359838

O=S(=O)([O-])c1ccccc1O.O=S(=O)([O-])c1ccccc1O.[Ca+2]

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Phenolsulphonic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 known ✓ P23219 1/20 0.57
PKLR P30613 4/20 0.48
DUSP5 Q16690 1/20 0.44
NR4A1 P22736 1/20 0.44
CDK2 P24941 1/20 0.42
PTPN1 P18031 2/20 0.42
PGAM1 P18669 2/20 0.42
CA2 P00918 3/20 0.41
CA4 P22748 3/20 0.41
POLB P06746 2/20 0.41
KDM4E B2RXH2 2/20 0.41
CA12 O43570 2/20 0.41
ALDH1A1 P00352 2/20 0.41
MAPT P10636 2/20 0.41
HPGD P15428 2/20 0.41
CA5A P35218 2/20 0.41
HSD17B10 Q99714 2/20 0.41
CA14 Q9ULX7 2/20 0.41
CA5B Q9Y2D0 2/20 0.41
TDP1 Q9NUW8 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenolsulphonic Acid SCHEMBL3170291 0.98 PTGS1 (0.55) PTGS1PKLRDUSP5NR4A1CDK2
Phenolsulphonic Acid SCHEMBL3173341 0.98 PTGS1 (0.55) PTGS1PKLRDUSP5NR4A1CDK2
Phenolsulphonic Acid SCHEMBL3176513 0.95 PTGS1 (0.52) PTGS1PKLRDUSP5NR4A1CDK2
Phenolsulphonic Acid SCHEMBL237346 0.95 PTGS1 (0.52) PTGS1PKLRDUSP5NR4A1CDK2
Phenolsulphonic Acid SCHEMBL2967983 0.95 PTGS1 (0.52) PTGS1PKLRDUSP5NR4A1CDK2
Phenolsulphonic Acid SCHEMBL1394635 0.95 PTGS1 (0.52) PTGS1PKLRDUSP5NR4A1CDK2
Phenolsulphonic Acid SCHEMBL5404273 0.95 PTGS1 (0.52) PTGS1PKLRDUSP5NR4A1CDK2
Phenolsulphonic Acid SCHEMBL158699 0.95 PKLR (0.53) PTGS1PKLRDUSP5NR4A1CDK2
Phenolsulphonic Acid SCHEMBL20534105 0.95 PTGS1 (0.52) PTGS1PKLRDUSP5NR4A1CDK2
Phenolsulphonic Acid SCHEMBL1857993 0.95 PTGS1 (0.52) PTGS1PKLRDUSP5NR4A1CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117185738-A Building solid waste recycled concrete and processing technology thereof 山西熙在高新材料有限公司 2023-12-08 CN claimed
CN-110041890-A Compound dust suppressant of biology base and preparation method thereof 中国葛洲坝集团易普力股份有限公司 2019-07-23 CN claimed
CN-105420736-B A kind of vinyl chloride converter high-temperature corrosion inhibitor and its preparation and application 常州中南化工有限公司 2018-09-07 CN claimed
CN-108042381-A Paeonol derivative is in skin anti-inflammatory, anti-acne, whitening, nti-freckle and the application in dispelling pigmentation 陕西医药控股医药研究院有限公司 2018-05-18 CN claimed
EP-2031008-B1 REACTION ACCELERATOR FOR CONDUCTIVE POLYMER SYNTHESIS, CONDUCTIVE POLYMER AND SOLID ELECTROLYTIC CAPACITOR TAYCA CORP (JP) 2016-10-05 EP claimed
CN-105796513-A Calcium dobesilate pharmaceutical composition 江苏万邦生化医药股份有限公司 2016-07-27 CN claimed
CN-105418466-A Calcium dobesilate compound and preparation method thereof SHIJIAZHUANG HUAXIN PHARMACEUTICAL CO LTD 2016-03-23 CN claimed
CN-102112000-B Anti-allergen combinations of calcium and lanthanum salts JANSSEN PHARMACEUTICA NV 2015-02-25 CN claimed
CN-103877038-A Calcium dobesilate dispersible tablet and preparation method thereof JIANGSU WANBANG BIOPHARMACEUTICALS CO LTD 2014-06-25 CN claimed
US-20130280199-A1 COSMETIC COMPOSITION COMPRISING AT LEAST ONE HYGROSCOPIC SALT, AT LEAST ONE AROMATIC POLYOL ETHER AND AT LEAST ONE DIOL, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2013-10-24 US claimed
US-20110135750-A1 ANTI-ALLERGEN COMBINATIONS OF CALCIUM AND LANTHANUM BYLEMANS DANY LEOPOLD JOZEFIEN 2011-06-09 US claimed
EP-2323485-A1 ANTI-ALLERGEN COMBINATIONS OF CALCIUM AND LANTHANUM SALTS Janssen Pharmaceutica, N.V. (BE) 2011-05-25 EP claimed
CN-101880248-A Synthetic reaction of calcium dobesilate hydrate NINGXIA KANGYA PHARMACEUTICAL CO LTD 2010-11-10 CN claimed
WO-2010015697-A1 ANTI-ALLERGEN COMBINATIONS OF CALCIUM AND LANTHANUM SALTS JANSSEN PHARMACEUTICA NV (BE) 2010-02-11 WO claimed
US-7651639-B2 Conductive polymer and solid electrolytic capacitor using the same TAYCA CORPORATION (JP) 2010-01-26 US claimed
CN-1259042-C Calcium phenol sulfonate dispersive tablets and their preparation XU XINSHENG (CN) 2006-06-14 CN claimed
CN-1214002-C Process for synthesizing hydrate of calcium phenolsulfonate LIJUN PHARMACEUTICAL CO LTD XI (CN) 2005-08-10 CN claimed
CN-1582910-A Calcium phenol sulfonate dispersive tablets and their preparation XU XINSHENG (CN) 2005-02-23 CN claimed
CN-1359897-A Process for synthesizing hydrate of calcium phenolsulfonate LIJUN PHARMACEUTICAL CO LTD XI (CN) 2002-07-24 CN claimed
US-6071417-A ADDITION OF ALKALI POLYPHOSPHATES TO AN AQUEOUS SOLUTION CONTAINING RESIDUAL AMOUNTS OF CATIONIC, ANIONIC, OR AMPHOTERIC WATER-SOLUBLE MACROMOLECULAR COMPOUNDS, FORMATION OF INSOLUBLE COMPLEXES OF THE ALKALI POLYPHOSPHATE KURITA WATER INDUSTRIES, LTD. (JP) 2000-06-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130280199-A1 COSMETIC COMPOSITION COMPRISING AT LEAST ONE HYGROSCOPIC SALT, AT LEAST ONE AROMATIC POLYOL ETHER AND AT LEAST ONE DIOL, AND COSMETIC TREATMENT PROCESS KRT18, DSG1, H1-0 PTGS1 3955/4885PKLR 628/4885DUSP5 2155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.