Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | ALPG | P10696 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | VNN1 | O95497 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8049735 | 0.91 | ALDH1A1 (0.43) | LTA4HSMN1; SMN2LMNAALDH1A1RAB9A | |
| SCHEMBL3348361 | 0.85 | GRM5 (0.43) | APPNPC1RAB9AFFAR1 | |
| SCHEMBL3604322 | 0.85 | VNN1 (0.44) | LTA4HSMN1; SMN2LMNAALDH1A1ALPG | |
| SCHEMBL8037855 | 0.84 | ALDH1A1 (0.50) | SMN1; SMN2LMNAALDH1A1NPC1TDP1 | |
| SCHEMBL7717354 | 0.83 | LTA4H (0.57) | LTA4HAPPSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL7715045 | 0.83 | LTA4H (0.57) | LTA4HAPPSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL7716924 | 0.83 | LTA4H (0.57) | LTA4HAPPSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL712228 | 0.83 | GRM5 (0.46) | APPFFAR1 | |
| SCHEMBL6132177 | 0.80 | PTPN11 (0.50) | ALDH1A1TDP1RAB9AHPGDKDM4E | |
| SCHEMBL14908434 | 0.80 | RAB9A (0.51) | SMN1; SMN2LMNAALDH1A1NPC1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678873-B1 | Acetylene-terminated hyperbranched poly(arylene-ether-ketone-imides) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2010-03-16 | — | — | US | disclosed |