Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 2/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | ALPG | P10696 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7716078 | 0.86 | ATM (0.48) | VNN1MAPK14LTA4HGRM5SMN1; SMN2 | |
| SCHEMBL3603052 | 0.85 | LTA4H (0.50) | VNN1LTA4HSMN1; SMN2LMNAALPG | |
| SCHEMBL6545360 | 0.83 | ATM (0.46) | VNN1MAPK14LTA4HGRM5SMN1; SMN2 | |
| SCHEMBL7715052 | 0.83 | ATM (0.46) | VNN1MAPK14LTA4HGRM5SMN1; SMN2 | |
| SCHEMBL4301156 | 0.82 | L3MBTL1 (0.53) | VNN1MAPK14LTA4HSMN1; SMN2LMNA | |
| SCHEMBL7716935 | 0.80 | VNN1 (0.47) | VNN1MAPK14GRM5ATMTDP1 | |
| SCHEMBL1637191 | 0.79 | ABCC9 (0.44) | VNN1MAPK14SMN1; SMN2LMNACTSL | |
| SCHEMBL9545806 | 0.79 | CA12 (0.44) | GRM5HPGDTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL29411036 | 0.79 | CA12 (0.44) | GRM5HPGDTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL9477603 | 0.79 | ACACB (0.47) | GRM5SMN1; SMN2LMNAHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678873-B1 | Acetylene-terminated hyperbranched poly(arylene-ether-ketone-imides) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2010-03-16 | — | — | US | claimed |
| US-7678873-B1 | Acetylene-terminated hyperbranched poly(arylene-ether-ketone-imides) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2010-03-16 | — | — | US | disclosed |