Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.34 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL150096 | 0.84 | MAOB (0.32) | ACHENPC1RAB9ANFE2L2AR | |
| SCHEMBL1491042 | 0.81 | ALDH1A1 (0.38) | ALDH1A1MEN1NPC1MAPK1RAB9A | |
| SCHEMBL435279 | 0.81 | CYP1A2 (0.38) | MEN1NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL11288386 | 0.81 | LMNA (0.39) | NPC1PKMMAPK1RAB9AKMT2A | |
| SCHEMBL12815215 | 0.80 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL10494072 | 0.79 | TAAR1 (0.41) | ACHEMEN1KMT2A | |
| SCHEMBL15757626 | 0.78 | LMNA (0.34) | ALDH1A1 | |
| SCHEMBL434023 | 0.77 | NOTUM (0.35) | ALDH1A1ACHEMEN1NPC1PKM | |
| SCHEMBL6189267 | 0.77 | CYP1A2 (0.33) | ALDH1A1 | |
| SCHEMBL4275387 | 0.77 | HSD17B1 (0.47) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109153682-B | Novel pyrazine compounds with oxygen, sulfur and nitrogen linkers for the treatment of infectious diseases | 豪夫迈·罗氏有限公司 | 2021-05-25 | — | — | CN | claimed |
| US-5698169-A | USING DICARBOLLIDE OR DICARBAEXTRANIDE COMPLEX; ION EXCHANGING | COREMETALS RESEARCH, INC. (US) | 1997-12-16 | — | — | US | claimed |
| US-5666642-A | DICARBOLIDES | COREMETALS RESEARCH, INC. (US) | 1997-09-09 | — | — | US | claimed |
| WO-1996039702-A2 | METHODS AND AGENTS FOR THE EXTRACTION OF CESIUM AND STRONTIUM FROM NUCLEAR WASTE | COREMETALS RESEARCH, INC. (US) | 1996-12-12 | — | — | WO | claimed |
| WO-1996033132-A1 | EXTRACTION OF CESIUM AND STRONTIUM IONS FROM NUCLEAR WASTE | COREMETALS RESEARCH, INC. (US) | 1996-10-24 | — | — | WO | claimed |
| US-11969002-B2 | Savoury and mouthfulness taste enhancers | LUCTA, S.A. (ES) | 2024-04-30 | — | — | US | disclosed |
| EP-3864012-B1 | SAVOURY AND MOUTHFULNESS TASTE ENHANCERS | LUCTA S A (ES) | 2023-09-13 | — | — | EP | disclosed |
| CN-107793409-B | Dihydropyrimidine compound and application thereof in medicine | 广东东阳光药业有限公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-110088103-B | Novel tetrahydropyridopyrimidine compounds for the treatment and prophylaxis of hepatitis b virus infection | 豪夫迈·罗氏有限公司 | 2022-04-12 | — | — | CN | disclosed |
| US-20210337850-A1 | SAVOURY AND MOUTHFULNESS TASTE ENHANCERS | LUCTA, S.A. (ES) | 2021-11-04 | — | — | US | disclosed |
| EP-3864012-A1 | SAVOURY AND MOUTHFULNESS TASTE ENHANCERS | Lucta, S.A. (ES) | 2021-08-18 | — | — | EP | disclosed |
| CN-109153682-B | Novel pyrazine compounds with oxygen, sulfur and nitrogen linkers for the treatment of infectious diseases | 豪夫迈·罗氏有限公司 | 2021-05-25 | — | — | CN | disclosed |
| WO-2001047875-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-07-05 | — | — | WO | disclosed |
| WO-2000056800-A1 | TWO-COMPONENT PREPARATIONS CONTAINING EPOXY COMPOUNDS | 3M ESPE AG (DE) | 2000-09-28 | — | — | WO | disclosed |
| EP-1028945-A1 | SUBSTITUTED PYRIDINE COMPOUNDS AS ANTI-INFLAMMATORY AGENTS | Amgen Inc. (US) | 2000-08-23 | — | — | EP | disclosed |
| WO-1999024404-A1 | SUBSTITUTED PYRIDINE COMPOUNDS AS ANTI-INFLAMMATORY AGENTS | AMGEN INC. (US) | 1999-05-20 | — | — | WO | disclosed |
| US-4551464-A | AND SULFIMINO CARBOSTYRILS | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1985-11-05 | — | — | US | disclosed |
| EP-0071150-B1 | SULFIMINES, THEIR SALTS AND THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1985-07-03 | — | — | EP | disclosed |
| US-4442111-A | Antithrombotic sulfimino and sulfoximino indolinones-2 | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-04-10 | — | — | US | disclosed |
| EP-0071150-A1 | Sulfimines, their salts and their preparation, and pharmaceutical compositions containing them | Dr. Karl Thomae GmbH (DE) | 1983-02-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210337850-A1 | SAVOURY AND MOUTHFULNESS TASTE ENHANCERS | KCNJ6, TAS1R1, TAS2R5 | ALDH1A1 1833/4885SLC22A2 2920/4885SLC22A1 3012/4885 |
| US-11969002-B2 | Savoury and mouthfulness taste enhancers | TAS1R1, KCNJ6, KCNJ5 | ALDH1A1 1527/4885SLC22A2 3044/4885SLC22A1 3033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.