SCHEMBL360858

SCHEMBL360858

CC1CC(=O)OCC(C)(C)C1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
ALDH1A1 P00352 2/20 0.33
CRBN Q96SW2 1/20 0.33
GABRP O00591 1/20 0.32
GABRD O14764 1/20 0.32
GABRA1 P14867 1/20 0.32
GABRB1 P18505 1/20 0.32
GABRG2 P18507 1/20 0.32
GABRB3 P28472 1/20 0.32
GABRA5 P31644 1/20 0.32
GABRA3 P34903 1/20 0.32
GABRA2 P47869 1/20 0.32
GABRB2 P47870 1/20 0.32
GABRA4 P48169 1/20 0.32
GABRE P78334 1/20 0.32
GABRA6 Q16445 1/20 0.32
GABRG1 Q8N1C3 1/20 0.32
GABRG3 Q99928 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6344526 0.72 CYP2C19 (0.35) ALDH1A1AR
SCHEMBL13176256 0.70
SCHEMBL13697409 0.70 SMN1; SMN2 (0.37) SMN1; SMN2ALDH1A1CRBN
SCHEMBL9881076 0.70 SMN1; SMN2 (0.37) SMN1; SMN2CRBNGABRPGABRDGABRA1
SCHEMBL13697404 0.70 SMN1; SMN2 (0.37) SMN1; SMN2ALDH1A1CRBN
SCHEMBL10431444 0.70 SMN1; SMN2 (0.37) SMN1; SMN2ALDH1A1CRBN
SCHEMBL3412400 0.67
SCHEMBL11443083 0.67 GABRP (0.38) TDP1SMN1; SMN2ALDH1A1GABRPGABRD
SCHEMBL7113337 0.67 LMNA (0.45) TDP1SMN1; SMN2ALDH1A1GABRPGABRD
SCHEMBL45956 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 270 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240115771-A1 3D-PRINTED SCAFFOLDS OF PEPTIDE CONJUGATE POLYMER LEHIGH UNIVERSITY 2024-04-11 US claimed
WO-2022207920-A1 MULTIBRANCHED POLYMERS, COMPOSITIONS COMPRISING SAME, METHODS FOR PREPARING SAME, AND USE THEREOF IN ELECTROCHEMISTRY SCE FRANCE (FR) 2022-10-06 WO claimed
EP-2488567-B1 PROCESS FOR MAKING POLYESTER OR COPOLYESTER FROM LACTONES EVONIK DEGUSSA GMBH (DE) 2015-05-06 EP claimed
US-20120202966-A1 METHOD FOR PRODUCING POLYESTERS AND CO-POLYESTERS FROM LACTONES EVONIK DEGUSSA GMBH (DE) 2012-08-09 US claimed
US-20100131064-A1 BIORESORBABLE POLYMER RECONSTITUTED BONE AND METHODS OF FORMATION THEREOF UNIVERSITY OF NEBRASKA (US) 2010-05-27 US claimed
US-20090092801-A1 NONAQUEOUS INKJET INK, INK COMPOSITION FOR INKJET RECORDING, AND SUBSTRATE FOR COLOR FILTER TOYO INK MANUFACTURING CO., LTD. (JP) 2009-04-09 US claimed
EP-1778760-A4 BIORESORBABLE COMPOSITES AND METHOD OF FORMATION THEREOF UNIV NEBRASKA (US) 2009-01-21 EP claimed
EP-2007317-A2 BIORESORBABLE POLYMER RECONSTITUTED BONE AND METHODS OF FORMATION THEREOF University Of Nebraska (US) 2008-12-31 EP claimed
US-20080200638-A1 Bioresorbable Composites and Method of Formation Thereof NATIONAL SCIENCE FOUNDATION 2008-08-21 US claimed
WO-2008095083-A1 BIORESORBABLE POLYMER/CALCIUM SULFATE COMPOSITES AND METHOD OF FORMATION THEREOF BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) 2008-08-07 WO claimed
WO-2007140325-A2 BIORESORBABLE POLYMER RECONSTITUTED CERAMIC MATRICES AND METHODS OF FORMATION THEREOF UNIVERSITY OF NEBRASKA OFFICE OF TECHNOLOGY DEVELOPMENT (US) 2007-12-06 WO claimed
WO-2007117499-A2 BIORESORBABLE POLYMER RECONSTITUTED BONE AND METHODS OF FORMATION THEREOF UNIVERSITY OF NEBRASKA (US) 2007-10-18 WO claimed
EP-1778760-A1 BIORESORBABLE COMPOSITES AND METHOD OF FORMATION THEREOF University of Nebraska (US) 2007-05-02 EP claimed
WO-2006015316-A1 BIORESORBABLE COMPOSITES AND METHOD OF FORMATION THEREOF UNIVERSITY OF NEBRASKA (US) 2006-02-09 WO claimed
US-20040068059-A1 Aliphatic polyester copolymer and process for producing the same, biodegradable resin molding based on aliphatic polyester, and lactone-containing resin DAICEL CHEMICAL INDUSTRIES LTD. (JP) 2004-04-08 US claimed
EP-1354908-A1 ALIPHATIC POLYESTER COPOLYMER AND PROCESS FOR PRODUCING THE SAME, BIODEGRADABLE RESIN MOLDING BASED ON ALIPHATIC POLYESTER, AND LACTONE-CONTAINING RESIN DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) 2003-10-22 EP claimed
US-12600857-B2 Polyether block amide-poly(meth)acrylate foams EVONIK OPERATIONS GMBH (DE) 2026-04-14 US disclosed
US-12565559-B2 Water-dispersible modified polyisocyanates COVESTRO DEUTSCHLAND AG (DE) 2026-03-03 US disclosed
EP-0459913-A2 Composition comprising a novel alicyclic compound, a process for the preparation thereof, a curable composition, and a photo-polymerizable composition DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1991-12-04 EP disclosed
EP-0409735-A1 A polycaprolactone polyol and hydrolysis resistant polyurethane resins prepared therefrom DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1991-01-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12600857-B2 Polyether block amide-poly(meth)acrylate foams MMAB, EIF2B1, EIF2B3 GAA 4820/4885TDP1 2320/4885SMN1; SMN2 2580/4885
US-12565559-B2 Water-dispersible modified polyisocyanates INTS9, PRMT9, IPO9 GAA 4557/4885TDP1 2119/4885SMN1; SMN2 710/4885
US-20100131064-A1 BIORESORBABLE POLYMER RECONSTITUTED BONE AND METHODS OF FORMATION THEREOF BMP2, PTH1R, BMP4 GAA 1810/4885TDP1 4670/4885SMN1; SMN2 4870/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.