Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.44 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.43 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | F11 | P03951 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3606029 | 0.99 | OPRM1 (0.44) | OPRM1OPRK1SOAT2ACAT1SOAT1 | |
| SCHEMBL3609202 | 0.87 | PPARD (0.42) | OPRM1OPRK1PPARDPPARGPPARA | |
| SCHEMBL3611181 | 0.85 | PPARD (0.44) | OPRM1OPRK1SOAT2ACAT1SOAT1 | |
| SCHEMBL3617469 | 0.84 | ACE (0.43) | SOAT2ACAT1SOAT1PPARDPPARG | |
| Hydrochloric Acid SCHEMBL3602370 | 0.84 | PPARD (0.43) | OPRM1OPRK1SOAT2ACAT1SOAT1 | |
| SCHEMBL3598872 | 0.80 | HSP90AA1 (0.41) | OPRM1OPRK1SOAT2ACAT1SOAT1 | |
| SCHEMBL3612962 | 0.80 | HTR1A (0.39) | SOAT2ACAT1SOAT1PPARDPPARG | |
| Hydrochloric Acid SCHEMBL3601036 | 0.79 | PPARD (0.51) | PPARDPPARGPPARAHDAC1HDAC2 | |
| SCHEMBL3612877 | 0.79 | OPRM1 (0.42) | OPRM1OPRK1PPARDPPARGPPARA | |
| SCHEMBL3601495 | 0.78 | XIAP (0.45) | F11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100016307-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2010-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016307-A1 | NOVEL COMPOUNDS | MET, HGF, HGFAC | OPRM1 209/4885OPRK1 600/4885SOAT2 2390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.