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Sugi Predict / Compounds / SCHEMBL3610083

SCHEMBL3610083

SCHEMBL3610083

N#Cc1ccc(C(=O)Nc2cccc(C(=O)O)c2)cc1

nearest known ligand 0.67

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ HPSE Q9Y251 1/20 0.67
▸ MEN1 O00255 2/20 0.66
▸ KMT2A Q03164 2/20 0.66
▸ NR1H4 Q96RI1 9/20 0.62
▸ F2 P00734 1/20 0.62
▸ PLG P00747 1/20 0.62
▸ PLAU P00749 1/20 0.62
▸ KLKB1 P03952 1/20 0.62
▸ PRSS1 P07477 1/20 0.62
▸ NPC1 O15118 1/20 0.62
▸ RAB9A P51151 1/20 0.62
▸ KCNK3 O14649 1/20 0.58
▸ KCNK9 Q9NPC2 1/20 0.58
▸ CYP11B1 P15538 1/20 0.58
▸ CYP11B2 P19099 1/20 0.58
▸ PKM P14618 1/20 0.55
▸ L3MBTL1 Q9Y468 1/20 0.55
▸ HTT P42858 1/20 0.55
▸ CREBBP Q92793 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2105154 0.99 HPSE (0.65) HPSEMEN1KMT2ANR1H4F2
SCHEMBL9249052 0.87 HPSE (0.84) HPSEMEN1KMT2ANR1H4NPC1
SCHEMBL2105152 0.87 KMT2A (0.60) HPSEMEN1KMT2AF2PLG
Hydrochloric Acid SCHEMBL2104599 0.87 HTT (0.60) HPSEMEN1KMT2ANR1H4F2
SCHEMBL12700258 0.87 MEN1 (0.69) HPSEMEN1KMT2AF2PLG
SCHEMBL9339487 0.86 P2RY14 (0.60) MEN1KMT2AF2PLGPLAU
SCHEMBL2832357 0.86 KMT2A (0.59) MEN1KMT2AF2PLGPLAU
SCHEMBL15904226 0.85 HPSE (0.67) HPSEMEN1KMT2ANR1H4NPC1
SCHEMBL2838977 0.85 RAB9A (0.72) MEN1KMT2AF2PLGPLAU
SCHEMBL3190254 0.84 MEN1 (0.68) MEN1KMT2AF2PLGPLAU

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12310944-B2 Selective butyrylcholinesterase inhibitor or pharmaceutically acceptable salt thereof, preparation method and use thereof CHINA PHARMACEUTICAL UNIVERSITY (CN) 2025-05-27 — — US disclosed
US-20230165833-A1 Selective Butyrylcholinesterase Inhibitor or Pharmaceutically Acceptable Salt Thereof, Preparation Method and Use Thereof CHINA PHARMACEUTICAL UNIVERSITY (CN) 2023-06-01 — — US disclosed
US-11034648-B2 Cystobactamide derivatives HELMHOLTZ-ZENTRUM FÜR (DE) 2021-06-15 — — US disclosed
US-11034648-B2 Cystobactamide derivatives HELMHOLTZ-ZENTRUM FÜR (DE) 2021-06-15 — — US disclosed
WO-2021042410-A1 SELECTIVE BUTYRYLCHOLINESTERASE INHIBITOR OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 中国药科大学 2021-03-11 — — WO disclosed
CN-110627767-B Selective butyrylcholinesterase inhibitor or pharmaceutically acceptable salt thereof, preparation method and application thereof 中国药科大学 2020-08-25 — — CN disclosed
EP-3672937-A1 NOVEL CYSTOBACTAMIDE DERIVATIVES Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2020-07-01 — — EP disclosed
US-20200190020-A1 NOVEL CYSTOBACTAMIDE DERIVATIVES Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2020-06-18 — — US disclosed
US-20200190020-A1 NOVEL CYSTOBACTAMIDE DERIVATIVES Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2020-06-18 — — US disclosed
CN-110997627-A Novel cystobacter amide derivatives 亥姆霍兹感染研究中心有限公司 2020-04-10 — — CN disclosed
CN-110627767-A Selective butyrylcholinesterase inhibitor or pharmaceutically acceptable salt thereof, preparation method and application thereof 中国药科大学 2019-12-31 — — CN disclosed
WO-2019038405-A1 NOVEL CYSTOBACTAMIDE DERIVATIVES Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2019-02-28 — — WO disclosed
WO-2019038405-A1 NOVEL CYSTOBACTAMIDE DERIVATIVES Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2019-02-28 — — WO disclosed
EP-2046765-B1 INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2012-10-17 — — EP disclosed
US-20100048652-A1 INSECTICIDAL COMPOUNDS SYNGENTA CROP PROTECTION, INC. (US) 2010-02-25 — — US disclosed
EP-2046765-A1 INSECTICIDAL COMPOUNDS Syngeta Participations AG (CH) 2009-04-15 — — EP disclosed
WO-2008012027-A1 INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2008-01-31 — — WO disclosed
US-5039805-A Novel benzoic and phenylacetic acid derivatives HOFFMANN-LA ROCHE INC. (US) 1991-08-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11034648-B2 Cystobactamide derivatives CTH, CBS, SLC7A11 HPSE 3876/4885MEN1 2023/4885KMT2A 2115/4885
US-20200190020-A1 NOVEL CYSTOBACTAMIDE DERIVATIVES CTH, CBS, SLC7A11 HPSE 3851/4885MEN1 2097/4885KMT2A 2307/4885
US-20230165833-A1 Selective Butyrylcholinesterase Inhibitor or Pharmaceutically Acceptable Salt Thereof, Preparation Method and Use Thereof BCHE, ACHE, BACE1 HPSE 1091/4885MEN1 2484/4885KMT2A 2073/4885
US-12310944-B2 Selective butyrylcholinesterase inhibitor or pharmaceutically acceptable salt thereof, preparation method and use thereof BCHE, ACHE, BACE1 HPSE 1291/4885MEN1 2495/4885KMT2A 2226/4885
US-20100048652-A1 INSECTICIDAL COMPOUNDS ACHE, CHRM1, CHRM2 HPSE 4664/4885MEN1 677/4885KMT2A 2740/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.