Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3610966 | 1.00 | MIF (0.67) | MIFNPSR1TDO2CA1CA2 | |
| SCHEMBL716630 | 0.81 | MIF (0.71) | MIFTDO2CA1CA2NFKB1 | |
| SCHEMBL1920415 | 0.81 | MIF (0.71) | MIFTDO2CA1CA2NFKB1 | |
| SCHEMBL29407005 | 0.81 | MIF (0.71) | MIFTDO2CA1CA2NFKB1 | |
| SCHEMBL716629 | 0.81 | MIF (0.71) | MIFTDO2CA1CA2NFKB1 | |
| SCHEMBL3027813 | 0.80 | ALDH1A1 (0.49) | MIFCA1CA2KDM4EHTT | |
| SCHEMBL3027810 | 0.80 | ALDH1A1 (0.49) | MIFCA1CA2KDM4EHTT | |
| Hydrochloric Acid SCHEMBL6822230 | 0.80 | MIF (0.69) | MIFTDO2CA1CA2NFKB1 | |
| SCHEMBL668852 | 0.80 | MIF (1.00) | MIFTDO2CA1CA2NFKB1 | |
| SCHEMBL668853 | 0.80 | MIF (1.00) | MIFTDO2CA1CA2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1916234-B1 | CYCLOPROPANECARBOXYLIC ACID COMPOUND | TAKEDA PHARMACEUTICAL (JP) | 2014-11-12 | — | — | EP | disclosed |
| US-7786165-B2 | Aminophenylpropanoic acid derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-31 | — | — | US | disclosed |
| US-20100144806-A1 | Cyclopropanecarboxylic Acid Compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-10 | — | — | US | disclosed |
| US-20080269220-A1 | Aminophenylpropanoic Acid Derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-10-30 | — | — | US | disclosed |
| EP-1916234-A1 | CYCLOPROPANECARBOXYLIC ACID COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2008-04-30 | — | — | EP | disclosed |
| EP-1726580-A1 | AMINOPHENYLPROPANOIC ACID DERIVATIVE | Takeda Pharmaceutical Company Limited (JP) | 2006-11-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269220-A1 | Aminophenylpropanoic Acid Derivative | GPR119, GPR55, GPR65 | MIF 2826/4885NPSR1 195/4885TDO2 2982/4885 |
| US-20100144806-A1 | Cyclopropanecarboxylic Acid Compound | GPR65, GPR34, GPR68 | MIF 1109/4885NPSR1 88/4885TDO2 4174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.