Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 1/20 | 0.37 |
| ▸ | KCNMA1 | Q12791 | 5/20 | 0.37 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.31 |
| ▸ | FABP3 | P05413 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3615403 | 0.81 | MEN1 (0.33) | MAPTKMT2ANPC1RAB9A | |
| SCHEMBL3621237 | 0.80 | CXCR2 (0.36) | CXCR2KCNMA1WDR5MAPTGAA | |
| SCHEMBL3613839 | 0.77 | MAPT (0.40) | MAPTKDM4EKMT2APOLBALDH1A1 | |
| SCHEMBL3617351 | 0.69 | MAPK14 (0.34) | GAAALDH1A1 | |
| SCHEMBL3619699 | 0.69 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL5764585 | 0.68 | PDK1 (0.44) | — | |
| SCHEMBL3624434 | 0.68 | NPSR1 (0.40) | MAPTGAAKDM4EPOLBALDH1A1 | |
| SCHEMBL5764100 | 0.68 | PDK1 (0.44) | — | |
| SCHEMBL3618237 | 0.66 | KMT2A (0.35) | MAPTKDM4EKMT2APOLBALDH1A1 | |
| SCHEMBL11091688 | 0.64 | CXCR2 (0.57) | CXCR2KCNMA1MAPTGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100267796-A1 | THERAPEUTIC AGENT FOR IRRITABLE BOWEL SYNDROME | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2010-10-21 | — | — | US | disclosed |
| EP-2077122-A1 | THERAPEUTIC AGENTS FOR IRRITABLE BOWEL SYNDROME | Kyowa Hakko Kirin Co., Ltd. (JP) | 2009-07-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267796-A1 | THERAPEUTIC AGENT FOR IRRITABLE BOWEL SYNDROME | SLC10A2, ADORA3, HRH2 | CXCR2 915/4885KCNMA1 2178/4885WDR5 943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.