SCHEMBL3625337

SCHEMBL3625337

CC(C)C(=O)NS(=O)(=O)c1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)ccc1Cl

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.32
LMNA P02545 2/20 0.32
ALDH1A1 P00352 1/20 0.32
GSTO1 P78417 2/20 0.31
NOTUM Q6P988 1/20 0.31
PTPN1 P18031 1/20 0.31
MCL1 Q07820 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
GAA P10253 1/20 0.30
TP53 P04637 1/20 0.30
MAPT P10636 1/20 0.30
TRPA1 O75762 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8936370 0.87 MEN1 (0.39) LMNAALDH1A1GSTO1NOTUMMCL1
SCHEMBL3555928 0.81 TSHR (0.34) NPSR1ALDH1A1NOTUMTP53MAPT
SCHEMBL3545755 0.80 MMP2 (0.36) LMNAALDH1A1MAPTKDM4E
SCHEMBL8936415 0.78 GSTO1 (0.41) LMNAALDH1A1GSTO1SMN1; SMN2GAA
SCHEMBL8936351 0.78 ALDH1A1 (0.32) LMNAALDH1A1GSTO1NOTUMSMN1; SMN2
SCHEMBL8936385 0.78 GSTO1 (0.45) LMNAALDH1A1GSTO1SMN1; SMN2GAA
SCHEMBL6049373 0.76 SCN9A (0.36) SMN1; SMN2KDM4E
SCHEMBL8464575 0.76 MCL1 (0.35) MCL1TP53MAPT
SCHEMBL3546133 0.76 MEN1 (0.31) ALDH1A1
SCHEMBL31442410 0.75 COMT (0.37) ALDH1A1NOTUMSMN1; SMN2GAATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7741485-B2 Benzenesulphonamide derivatives as herbicides or desiccant/defoliant compounds BASF AKTIENGESELLSCHAFT (DE) 2010-06-22 US disclosed
US-7741485-B2 Benzenesulphonamide derivatives as herbicides or desiccant/defoliant compounds BASF AKTIENGESELLSCHAFT (DE) 2010-06-22 US disclosed
US-7741485-B2 Benzenesulphonamide derivatives as herbicides or desiccant/defoliant compounds BASF AKTIENGESELLSCHAFT (DE) 2010-06-22 US disclosed
US-20060211577-A1 Benzenesulphonamide derivatives as herbicides or desiccant/defoliant compounds BASF AKTIENGESELLSCHAFT (DE) 2006-09-21 US disclosed
EP-1613607-A1 BENZENESULPHONAMIDE DERIVATIVES AS HERBICIDES OR DESICCANT/DEFOLIANT COMPOUNDS BASF Aktiengesellschaft (DE) 2006-01-11 EP disclosed
WO-2004089914-A1 BENZENESULPHONAMIDE DERIVATIVES AS HERBICIDES OR DESICCANT/DEFOLIANT COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2004-10-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060211577-A1 Benzenesulphonamide derivatives as herbicides or desiccant/defoliant compounds CBR3, CBR1, CNPY2 NPSR1 139/4885LMNA 2968/4885ALDH1A1 2179/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.