SCHEMBL8936385

SCHEMBL8936385

COCCNS(=O)(=O)c1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)ccc1Cl

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GSTO1 P78417 2/20 0.45
POLB P06746 4/20 0.43
L3MBTL1 Q9Y468 1/20 0.41
GAA P10253 3/20 0.41
SMN1; SMN2 Q16637 4/20 0.38
USP2 O75604 1/20 0.38
ALDH1A1 P00352 4/20 0.36
TSHR P16473 2/20 0.35
MEN1 O00255 1/20 0.35
PKM P14618 1/20 0.35
KMT2A Q03164 1/20 0.35
KDM4E B2RXH2 2/20 0.35
MAPT P10636 2/20 0.34
HTT P42858 1/20 0.34
LMNA P02545 2/20 0.34
NPC1 O15118 1/20 0.34
HPGD P15428 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8936370 0.84 MEN1 (0.39) GSTO1L3MBTL1SMN1; SMN2ALDH1A1TSHR
SCHEMBL8936419 0.82 GSTO1 (0.45) GSTO1POLBL3MBTL1SMN1; SMN2ALDH1A1
SCHEMBL3555928 0.80 TSHR (0.34) L3MBTL1ALDH1A1TSHRMEN1KMT2A
SCHEMBL3545755 0.79 MMP2 (0.36) L3MBTL1ALDH1A1TSHRMEN1KMT2A
SCHEMBL3625337 0.78 NPSR1 (0.32) GSTO1GAASMN1; SMN2ALDH1A1KDM4E
SCHEMBL8936415 0.77 GSTO1 (0.41) GSTO1POLBL3MBTL1GAASMN1; SMN2
SCHEMBL8466103 0.75 MCL1 (0.36) ALDH1A1TSHRMAPT
SCHEMBL3546133 0.75 MEN1 (0.31) L3MBTL1ALDH1A1TSHRMEN1KMT2A
SCHEMBL14571462 0.74 BRD9 (0.41) MAPTLMNA
SCHEMBL8936368 0.74 ALDH1A1 (0.34) GSTO1L3MBTL1SMN1; SMN2ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5486610-A HERBICIDE INTERMEDIATES UNIROYAL CHEMICAL COMPANY, INC. (US) 1996-01-23 US disclosed
US-5324854-A Herbicides UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-06-28 US disclosed
US-5169430-A Herbicides UNIROYAL CHEMICAL COMPANY, INC. (US) 1992-12-08 US disclosed