Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.32 |
| ▸ | ITGAL | P20701 | 1/20 | 0.32 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL446185 | 0.75 | ABCG2 (0.36) | CA2ABCG2ITGB2ICAM1ITGAL | |
| SCHEMBL6619829 | 0.74 | CA2 (0.36) | CA2ABCG2ITGB2ICAM1ITGAL | |
| SCHEMBL3625885 | 0.73 | CA2 (0.37) | CA2 | |
| SCHEMBL448546 | 0.69 | NISCH (0.44) | CA2ABCG2NISCH | |
| SCHEMBL6489987 | 0.69 | CA2 (0.37) | CA2 | |
| SCHEMBL21624268 | 0.69 | LMNA (0.35) | CA2NISCHMAOAMAOB | |
| SCHEMBL28504425 | 0.69 | CA2 (0.33) | CA2NISCHMAOAMAOB | |
| SCHEMBL11549002 | 0.69 | CA2 (0.37) | CA2 | |
| SCHEMBL11034100 | 0.66 | POLB (0.46) | CA2 | |
| SCHEMBL6002972 | 0.64 | HPGD (0.41) | CA2NISCHMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829585-B2 | Antifungal agent containing pyridine derivative | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-11-09 | — | — | US | disclosed |
| US-20090062348-A1 | Antifungal Agent Containing Pyridine Derivative | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-03-05 | — | — | US | disclosed |
| EP-1864980-A1 | ANTIFUNGAL AGENT CONTAINING PYRIDINE DERIVATIVE | Eisai R&D Management Co., Ltd. (JP) | 2007-12-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062348-A1 | Antifungal Agent Containing Pyridine Derivative | ERG28, SQOR, CYP51A1 | CA2 1156/4885ABCG2 121/4885ITGB2 3875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.