Phthalic Acid

Phthalic Acid

SCHEMBL3628205

O=C(O)c1ccccc1C(=O)O.OCc1ccccc1F

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.54
ALOX15 P16050 2/20 0.54
ALB P02768 1/20 0.50
FOLH1 Q04609 1/20 0.47
FABP3 P05413 1/20 0.47
CES2 O00748 1/20 0.47
CES1 P23141 1/20 0.47
KMT2A Q03164 3/20 0.46
CYP1A2 P05177 2/20 0.46
CYP2C19 P33261 1/20 0.46
GAA P10253 3/20 0.46
HPGD P15428 2/20 0.46
LMNA P02545 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
FABP4 P15090 1/20 0.46
MAPT P10636 2/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2C9 P11712 1/20 0.45
ALOX12 P18054 1/20 0.45
PTPN1 P18031 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL28094262 0.84 ALDH1A1 (0.49) ALDH1A1KMT2ALMNAMEN1KDM4E
SCHEMBL29963524 0.83
SCHEMBL20465748 0.83
SCHEMBL98875 0.83
SCHEMBL374696 0.81 FOLH1 (0.61) ALDH1A1ALOX15FOLH1KMT2AGAA
SCHEMBL6043201 0.79 FOLH1 (0.59) ALDH1A1ALOX15FOLH1KMT2AGAA
SCHEMBL8768476 0.79 FOLH1 (0.59) ALDH1A1ALOX15FOLH1KMT2AGAA
SCHEMBL1401459 0.78 MRGPRX4 (0.49) ALDH1A1ALOX15ALBFOLH1CES2
Phthalic Acid SCHEMBL3628700 0.78 ALDH1A1 (0.50) ALDH1A1ALOX15FOLH1FABP3KMT2A
SCHEMBL27631073 0.78 ALB (0.52) ALDH1A1ALOX15ALBFOLH1FABP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101287692-B Preparation method of optically active fluorobenzyl alcohol CENTRAL GLASS CO LTD 2012-06-06 CN disclosed
EP-1935866-B1 PROCESS FOR PRODUCING OPTICALLY ACTIVE FLUOROBENZYL ALCOHOL CENTRAL GLASS CO LTD (JP) 2011-12-14 EP disclosed
US-7795478-B2 Process for producing optically active fluorobenzyl alcohol CENTRAL GLASS COMPANY, LIMITED (JP) 2010-09-14 US disclosed
US-20090240087-A1 Process for Producing Optically Active Fluorobenzyl Alcohol CENTRAL GLASS COMPANY, LIMITED (JP) 2009-09-24 US disclosed
CN-101287692-A Preparation method of optically active fluorobenzyl alcohol CENTRAL GLASS CO LTD (JP) 2008-10-15 CN disclosed
EP-1935866-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE FLUOROBENZYL ALCOHOL Central Glass Company, Limited (JP) 2008-06-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090240087-A1 Process for Producing Optically Active Fluorobenzyl Alcohol ADH1A, ADH1C, ADH5 ALDH1A1 47/4885ALOX15 1031/4885ALB 2130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.