Phthalic Acid

Phthalic Acid

SCHEMBL3628700

O=C(O)c1ccccc1C(=O)O.OCc1ccccc1C(F)(F)F

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
FABP4 P15090 2/20 0.50
ALOX15 P16050 1/20 0.50
FABP3 P05413 1/20 0.50
POLQ O75417 1/20 0.49
EPHX2 P34913 1/20 0.48
TAS2R14 Q9NYV8 2/20 0.48
GAA P10253 3/20 0.47
LMNA P02545 2/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
PPARG P37231 1/20 0.45
PPARA Q07869 1/20 0.45
FOLH1 Q04609 1/20 0.44
IDO1 P14902 1/20 0.44
KDM4E B2RXH2 1/20 0.44
ATM Q13315 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
HPGD P15428 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL44837 0.84 IDO1 (0.57) ALDH1A1POLQKMT2AIDO1KDM4E
SCHEMBL29389277 0.84 IDO1 (0.57) ALDH1A1POLQKMT2AIDO1KDM4E
SCHEMBL3628696 0.81 ALDH1A1 (0.58) ALDH1A1FABP4FABP3POLQEPHX2
SCHEMBL30449216 0.81 LMNA (0.62) ALDH1A1FABP4ALOX15TAS2R14GAA
SCHEMBL221518 0.81 LMNA (0.62) ALDH1A1FABP4ALOX15TAS2R14GAA
Alcohol SCHEMBL28201640 0.80 LMNA (0.53) ALDH1A1FABP4ALOX15TAS2R14GAA
Alcohol SCHEMBL3628691 0.80 ALDH1A1 (0.52) ALDH1A1POLQTAS2R14LMNAPPARG
SCHEMBL9461001 0.79 LMNA (0.60) ALDH1A1FABP4ALOX15TAS2R14GAA
Hydrochloric Acid SCHEMBL2533965 0.79 LMNA (0.60) ALDH1A1FABP4ALOX15TAS2R14GAA
SCHEMBL29208535 0.79 LMNA (0.60) ALDH1A1FABP4ALOX15TAS2R14GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101287692-B Preparation method of optically active fluorobenzyl alcohol CENTRAL GLASS CO LTD 2012-06-06 CN disclosed
EP-1935866-B1 PROCESS FOR PRODUCING OPTICALLY ACTIVE FLUOROBENZYL ALCOHOL CENTRAL GLASS CO LTD (JP) 2011-12-14 EP disclosed
US-7795478-B2 Process for producing optically active fluorobenzyl alcohol CENTRAL GLASS COMPANY, LIMITED (JP) 2010-09-14 US disclosed
US-20090240087-A1 Process for Producing Optically Active Fluorobenzyl Alcohol CENTRAL GLASS COMPANY, LIMITED (JP) 2009-09-24 US disclosed
CN-101287692-A Preparation method of optically active fluorobenzyl alcohol CENTRAL GLASS CO LTD (JP) 2008-10-15 CN disclosed
EP-1935866-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE FLUOROBENZYL ALCOHOL Central Glass Company, Limited (JP) 2008-06-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090240087-A1 Process for Producing Optically Active Fluorobenzyl Alcohol ADH1A, ADH1C, ADH5 ALDH1A1 47/4885FABP4 219/4885ALOX15 1031/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.