Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3629097 | 1.00 | PDE10A (0.38) | PDE10AALDH1A1CYP1A2MAPTCYP2C9 | |
| SCHEMBL1508506 | 0.84 | MEN1 (0.45) | MAPTTBXAS1L3MBTL1LMNAKDM4E | |
| SCHEMBL1508505 | 0.84 | MEN1 (0.45) | MAPTTBXAS1L3MBTL1LMNAKDM4E | |
| SCHEMBL1100704 | 0.83 | TBXAS1 (0.34) | ALDH1A1MAPTCYP2C9CYP2C19TBXAS1 | |
| SCHEMBL1100701 | 0.83 | TBXAS1 (0.34) | ALDH1A1MAPTCYP2C9CYP2C19TBXAS1 | |
| SCHEMBL5861807 | 0.80 | TBXAS1 (0.39) | CYP2C9TBXAS1CYP3A4ESR1MEN1 | |
| SCHEMBL5860653 | 0.79 | TBXAS1 (0.39) | MAPTCYP2C9TBXAS1CYP3A4ESR1 | |
| SCHEMBL24587500 | 0.77 | ALDH1A1 (0.44) | ALDH1A1MAPTCYP2C9TBXAS1TSHR | |
| SCHEMBL7947844 | 0.77 | ALDH1A1 (0.44) | ALDH1A1MAPTCYP2C9TBXAS1TSHR | |
| SCHEMBL2272484 | 0.76 | GABRP (0.47) | ALDH1A1TBXAS1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7786165-B2 | Aminophenylpropanoic acid derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-31 | — | — | US | disclosed |
| US-20080269220-A1 | Aminophenylpropanoic Acid Derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269220-A1 | Aminophenylpropanoic Acid Derivative | GPR119, GPR55, GPR65 | PDE10A 743/4885ALDH1A1 495/4885CYP1A2 1304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.