Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7090393 | 0.90 | AR (0.64) | ARKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL10485801 | 0.85 | POLB (0.53) | KMT2AMAPTMEN1ALDH1A1GAA | |
| SCHEMBL1496592 | 0.85 | USP2 (0.60) | ARKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL12517404 | 0.84 | AR (0.58) | ARMAPTALDH1A1MAPK1HPGD | |
| SCHEMBL7088414 | 0.84 | AR (0.58) | ARKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL11256374 | 0.82 | PTGS1 (0.57) | ARMAPTALDH1A1HTTPOLB | |
| SCHEMBL11256369 | 0.82 | PTGS1 (0.57) | ARMAPTALDH1A1HTTPOLB | |
| SCHEMBL1496665 | 0.82 | POLB (0.57) | KMT2AMAPTMEN1ALDH1A1GAA | |
| SCHEMBL1496562 | 0.82 | CYP1A2 (0.60) | ARKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL6493739 | 0.82 | TSHR (0.69) | ARKMT2AMAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728179-B2 | Method for producing optically active alcohol compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-06-01 | — | — | US | disclosed |
| US-7591995-B2 | Cobalamin conjugates useful as imaging and therapeutic agents | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2009-09-22 | — | — | US | disclosed |
| EP-1380342-B1 | COMPLEX CATALYST, PROCESS FOR PRODUCING THE COMPLEX CATALYST, AND PROCESS FOR PRODUCING ALCOHOL DERIVATIVE WITH THE COMPLEX CATALYST | SUMITOMO CHEMICAL CO (JP) | 2009-07-01 | — | — | EP | disclosed |
| US-20090162281-A1 | Radionuclide labeling of Vitamin B12 and Co-enzymes thereof | COLLINS DOUGLAS A | 2009-06-25 | — | — | US | disclosed |
| US-20090012330-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-01-08 | — | — | US | disclosed |
| US-7462345-B2 | Radionuclide labeling of vitamin B12 and coenzymes thereof | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2008-12-09 | — | — | US | disclosed |
| WO-2008136850-A2 | COBALAMIN CONJUGATES USEFUL AS IMAGING AND THERAPEUTIC AGENTS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2008-11-13 | — | — | WO | disclosed |
| EP-1982972-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-10-22 | — | — | EP | disclosed |
| US-20070116644-A1 | COBALAMIN CONJUGATES USEFUL AS IMAGING AND THERAPEUTIC AGENTS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2007-05-24 | — | — | US | disclosed |
| US-20070110667-A1 | Radionuclide labeling of vitamin B12 and coenzymes thereof | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH, A MINNESOTA CORPORATION | 2007-05-17 | — | — | US | disclosed |
| EP-0883627-B1 | RADIONUCLIDE LABELING OF VITAMIN B12 AND COENZYMES THEREOF | MAYO FOUNDATION (US) | 2002-04-03 | — | — | EP | disclosed |
| WO-2001028595-A1 | COBALAMIN CONJUGATES USEFUL AS IMAGING AND THERAPEUTIC AGENTS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2001-04-26 | — | — | WO | disclosed |
| US-6211355-B1 | REACTING COBALAMIN COMPOUND WITH CHELATING COMPOUND TO COMPOUND USEFUL FOR IN VIVO IMAGING OF ORGANS AND TUMORS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH | 2001-04-03 | — | — | US | disclosed |
| US-6096290-A | ADMINISTERING COBALAMIN DERIVATIVES FOR IMAGING AND TREATMENT OF TUMORS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2000-08-01 | — | — | US | disclosed |
| US-6004533-A | COMPOUND USEFUL FOR IN VIVO IMAGING OF ORGANS AND TUMORS | MAYO MEDICAL VENTURES (US) | 1999-12-21 | — | — | US | disclosed |
| EP-0883627-A1 | RADIONUCLIDE LABELING OF VITAMIN B12 AND COENZYMES THEREOF | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 1998-12-16 | — | — | EP | disclosed |
| US-5739313-A | FOR IN VIVO IMAGING OF ORGANS AND TUMORS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1998-04-14 | — | — | US | disclosed |
| WO-1997018231-A1 | RADIONUCLIDE LABELING OF VITAMIN B12 AND COENZYMES THEREOF | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 1997-05-22 | — | — | WO | disclosed |
| EP-0054132-B1 | PYRIMIDONES, THEIR PREPARATION AND MEDICINES CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1984-10-10 | — | — | EP | disclosed |
| US-4379788-A | HYPOTENSIVES, ANTIARRHYTHMIA, B-BLOCKERS | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012330-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL COMPOUND | ADH1A, ADH1C, ADH5 | AR 230/4885KMT2A 1076/4885MAPT 4240/4885 |
| US-20070116644-A1 | COBALAMIN CONJUGATES USEFUL AS IMAGING AND THERAPEUTIC AGENTS | MMAB, SLC19A1, SLC19A2 | AR 4856/4885KMT2A 3214/4885MAPT 3139/4885 |
| US-20070110667-A1 | Radionuclide labeling of vitamin B12 and coenzymes thereof | MMAB, SLC39A14, SLC19A1 | AR 3262/4885KMT2A 4289/4885MAPT 3802/4885 |
| US-20090162281-A1 | Radionuclide labeling of Vitamin B12 and Co-enzymes thereof | HMBS, MMAB, HCCS | AR 4414/4885KMT2A 4289/4885MAPT 4701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.