SCHEMBL3630372

SCHEMBL3630372

C=CC[Si](CC=C)(CC=C)[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
TSHR P16473 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
CYP2C19 P33261 1/20 0.31
IDH1 O75874 1/20 0.30
NR1H2 P55055 1/20 0.30
NR1H3 Q13133 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL723613 0.78 ALDH1A1 (0.38) ALDH1A1TSHRL3MBTL1CYP2C19IDH1
SCHEMBL296966 0.76 ALDH1A1 (0.36) ALDH1A1TSHRL3MBTL1CYP2C19IDH1
SCHEMBL536223 0.76 ALDH1A1 (0.36) ALDH1A1TSHRL3MBTL1CYP2C19IDH1
SCHEMBL7118374 0.74 ALDH1A1 (0.35) ALDH1A1TSHRL3MBTL1CYP2C19IDH1
SCHEMBL5598557 0.73 ALDH1A1 (0.33) ALDH1A1TSHRL3MBTL1CYP2C19IDH1
SCHEMBL1493187 0.73 ALDH1A1 (0.33) ALDH1A1TSHRL3MBTL1CYP2C19IDH1
SCHEMBL9862805 0.73 NR1H2 (0.37) ALDH1A1TSHRL3MBTL1CYP2C19IDH1
SCHEMBL15301890 0.73 TSHR (0.33) ALDH1A1TSHRL3MBTL1CYP2C19IDH1
SCHEMBL3317837 0.73 NR1H2 (0.37) ALDH1A1TSHRL3MBTL1CYP2C19NR1H2
SCHEMBL5491545 0.73 ALDH1A1 (0.33) ALDH1A1TSHRL3MBTL1CYP2C19IDH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7674910-B2 Process for preparing diimine compounds BASELL POLYOLEFINE GMBH (DE) 2010-03-09 US disclosed
US-20070282110-A1 Process for Preparing Diimine Compounds BASELL POLYOLEFINE GMBH (DE) 2007-12-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070282110-A1 Process for Preparing Diimine Compounds PPIP5K2, DCPS, CD99 ALDH1A1 3071/4885TSHR 2696/4885L3MBTL1 4791/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.