Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL73339 | 0.82 | ALDH1A1 (0.33) | ALDH1A1TSHRL3MBTL1CYP2C19KDM4E | |
| SCHEMBL5493035 | 0.82 | ALDH1A1 (0.33) | ALDH1A1TSHRL3MBTL1CYP2C19KDM4E | |
| SCHEMBL27917212 | 0.78 | ALDH1A1 (0.31) | ALDH1A1TSHRL3MBTL1HPGD | |
| SCHEMBL15233854 | 0.78 | IDH1 (0.35) | ALDH1A1TSHRL3MBTL1IDH1 | |
| SCHEMBL9715855 | 0.78 | NR1H2 (0.35) | ALDH1A1TSHRL3MBTL1NR1H2NR1H3 | |
| SCHEMBL27825174 | 0.78 | ALDH1A1 (0.31) | ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL723613 | 0.78 | ALDH1A1 (0.38) | ALDH1A1TSHRL3MBTL1CYP2C19HPGD | |
| SCHEMBL536223 | 0.76 | ALDH1A1 (0.36) | ALDH1A1TSHRL3MBTL1CYP2C19HPGD | |
| SCHEMBL296966 | 0.76 | ALDH1A1 (0.36) | ALDH1A1TSHRL3MBTL1CYP2C19HPGD | |
| SCHEMBL14957505 | 0.75 | NR1H2 (0.30) | NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3066087-B1 | A PROCESS FOR THE PREPARATION OF OLOPATADINE AND SYLIL INTERMEDIATES THEREOF | LABORATORIO CHIMICO INT S P A (IT) | 2017-10-18 | — | — | EP | claimed |
| US-9708284-B2 | Process for the preparation of olopatadine and sylil intermediates thereof | LABORATORIO CHIMICO INTERNAZIONALE S.P.A. (IT) | 2017-07-18 | — | — | US | claimed |
| EP-3066087-A1 | A PROCESS FOR THE PREPARATION OF OLOPATADINE AND SYLIL INTERMEDIATES THEREOF | Laboratorio Chimico Internazionale S.p.A. (IT) | 2016-09-14 | — | — | EP | claimed |
| US-20160244425-A1 | A PROCESS FOR THE PREPARATION OF OLOPATADINE AND SYLIL INTERMEDIATES THEREOF | LABORATORIO CHIMICO INTERNAZIONALE S.P.A. (IT) | 2016-08-25 | — | — | US | claimed |
| WO-2015063579-A1 | A PROCESS FOR THE PREPARATION OF OLOPATADINE AND SYLIL INTERMEDIATES THEREOF | LABORATORIO CHIMICO INTERNAZIONALE S.P.A. (IT) | 2015-05-07 | — | — | WO | claimed |
| EP-3066087-B1 | A PROCESS FOR THE PREPARATION OF OLOPATADINE AND SYLIL INTERMEDIATES THEREOF | LABORATORIO CHIMICO INT S P A (IT) | 2017-10-18 | — | — | EP | disclosed |
| US-9708284-B2 | Process for the preparation of olopatadine and sylil intermediates thereof | LABORATORIO CHIMICO INTERNAZIONALE S.P.A. (IT) | 2017-07-18 | — | — | US | disclosed |
| EP-3066087-A1 | A PROCESS FOR THE PREPARATION OF OLOPATADINE AND SYLIL INTERMEDIATES THEREOF | Laboratorio Chimico Internazionale S.p.A. (IT) | 2016-09-14 | — | — | EP | disclosed |
| US-20160244425-A1 | A PROCESS FOR THE PREPARATION OF OLOPATADINE AND SYLIL INTERMEDIATES THEREOF | LABORATORIO CHIMICO INTERNAZIONALE S.P.A. (IT) | 2016-08-25 | — | — | US | disclosed |
| US-20150344735-A1 | Curable Silicone Composition, Cured Product Thereof, And Optical Semiconductor Device | DOW CORNING TORAY CO., LTD. (JP) | 2015-12-03 | — | — | US | disclosed |
| WO-2015063579-A1 | A PROCESS FOR THE PREPARATION OF OLOPATADINE AND SYLIL INTERMEDIATES THEREOF | LABORATORIO CHIMICO INTERNAZIONALE S.P.A. (IT) | 2015-05-07 | — | — | WO | disclosed |
| US-8871890-B2 | Curable resin composition and cured article | DAICEL CORPORATION (JP) | 2014-10-28 | — | — | US | disclosed |
| US-20030207928-A1 | Streptogramin derivatives, their preparation and compositions which contain them | AVENTIS PHARMA S.A. | 2003-11-06 | — | — | US | disclosed |
| US-6596717-B2 | As antibiotic agent | AVENTIS PHARMA S.A. (FR) | 2003-07-22 | — | — | US | disclosed |
| US-20020143041-A1 | Streptogramin derivatives, their preparation and compositions which contain them | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | US | disclosed |
| US-6288066-B1 | ANTIDIABETIC AGENTS; OXIDATION, HYDROLYSIS | AVENTIS PHARMA S.A. (FR) | 2001-09-11 | — | — | US | disclosed |
| US-5780661-A | Process for preparing allylsilane compound derivatives | DOW CORNING ASIA, LTD. (JP) | 1998-07-14 | — | — | US | disclosed |
| EP-0812848-A2 | Process for preparing allylsilane compound derivatives | DOW CORNING ASIA, Ltd. (JP) | 1997-12-17 | — | — | EP | disclosed |
| US-5098981-A | POLYORGANOSILOXANE | CHISSO CORPORATION (JP) | 1992-03-24 | — | — | US | disclosed |
| EP-0349920-A2 | Polyorganosiloxane | Chisso Corporation (JP) | 1990-01-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207928-A1 | Streptogramin derivatives, their preparation and compositions which contain them | MRPL21, SPG11, STT3B | ALDH1A1 4753/4885TSHR 3551/4885L3MBTL1 4860/4885 |
| US-20020143041-A1 | Streptogramin derivatives, their preparation and compositions which contain them | MRPL21, SPG11, STT3B | ALDH1A1 4753/4885TSHR 3551/4885L3MBTL1 4860/4885 |
| US-20160244425-A1 | A PROCESS FOR THE PREPARATION OF OLOPATADINE AND SYLIL INTERMEDIATES THEREOF | COMT, PNMT, OPRK1 | ALDH1A1 130/4885TSHR 3091/4885L3MBTL1 3846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.