Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.73 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.73 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.73 |
| ▸ | HTR2A | P28223 | 1/20 | 0.73 |
| ▸ | HTR2C | P28335 | 1/20 | 0.73 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.73 |
| ▸ | HRH1 | P35367 | 1/20 | 0.73 |
| ▸ | DRD3 | P35462 | 1/20 | 0.73 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.73 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.73 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.73 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.63 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.63 |
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.60 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.60 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1943942 | 1.00 | CHRM1 (0.73) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL1115851 | 1.00 | CHRM1 (0.73) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| Arundic Acid SCHEMBL277260 | 1.00 | CHRM1 (0.73) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| Arundic Acid SCHEMBL3450562 | 1.00 | CHRM1 (0.73) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL2489255 | 1.00 | CHRM1 (0.73) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL1115797 | 1.00 | CHRM1 (0.73) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL15499898 | 1.00 | CHRM1 (0.73) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL432094 | 1.00 | CHRM1 (0.73) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL1115939 | 1.00 | CHRM1 (0.73) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL1115977 | 1.00 | CHRM1 (0.73) | CHRM1AKR1A1CHRM3HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6605638-B1 | Treating multidrug resistant tumors; increasing drug bioavailability | D-PHARM LIMITED (IL) | 2003-08-12 | — | — | US | claimed |
| US-7687483-B2 | Derivatives of branch-chain lipophilic molecular and uses thereof | D-PHARM LTD. (IL) | 2010-03-30 | — | — | US | disclosed |
| EP-1305322-B1 | DERIVATIVES OF BRANCHED-CHAIN LIPOPHILIC MOLECULES AND USES THEREOF | DPHARM LTD (IL) | 2010-01-13 | — | — | EP | disclosed |
| US-7582678-B2 | Use of branched-chain fatty acids and derivatives thereof for the treatment of pain | D-PHARM LIMITED (IL) | 2009-09-01 | — | — | US | disclosed |
| EP-1419129-B1 | USE OF BRANCHED-CHAIN FATTY ACIDS AND DERIVATIVES THEREOF FOR THE TREATMENT OF PAIN | DPHARM LTD (IL) | 2008-12-03 | — | — | EP | disclosed |
| US-20070135381-A1 | Derivatives of branch-chain lipophilic molecular and uses thereof | D-PHARM LTD. (IL) | 2007-06-14 | — | — | US | disclosed |
| US-7186703-B2 | Derivatives of branched-chain lipophilic molecules and uses thereof | D-PHARM LTD. (IL) | 2007-03-06 | — | — | US | disclosed |
| EP-1419129-A4 | USE OF BRANCHED-CHAIN FATTY ACIDS AND DERIVATIVES THEREOF FOR THE TREATMENT OF PAIN | DPHARM LTD (IL) | 2006-05-10 | — | — | EP | disclosed |
| CN-1633440-A | Branched-chain lipophilic molecule derivatives and uses thereof | DPHARM LTD (IL) | 2005-06-29 | — | — | CN | disclosed |
| EP-1305322-A4 | DERIVATIVES OF BRANCHED-CHAIN LIPOPHILIC MOLECULES AND USES THEREOF | DPHARM LTD (IL) | 2005-04-13 | — | — | EP | disclosed |
| US-20040235949-A1 | Use of branched-chain fatty acids and derivatives thereof for the treatment of pain | D-PHARM LIMITED (IL) | 2004-11-25 | — | — | US | disclosed |
| EP-1419129-A2 | USE OF BRANCHED-CHAIN FATTY ACIDS AND DERIVATIVES THEREOF FOR THE TREATMENT OF PAIN | D-Pharm Limited (IL) | 2004-05-19 | — | — | EP | disclosed |
| US-20030186897-A1 | Derivatives of branched-chain lipophilic molecules and uses thereof | D-PHARM, LTD. (IL) | 2003-10-02 | — | — | US | disclosed |
| US-6605638-B1 | Treating multidrug resistant tumors; increasing drug bioavailability | D-PHARM LIMITED (IL) | 2003-08-12 | — | — | US | disclosed |
| EP-1305322-A2 | DERIVATIVES OF BRANCHED-CHAIN LIPOPHILIC MOLECULES AND USES THEREOF | D-Pharm Ltd. (IL) | 2003-05-02 | — | — | EP | disclosed |
| US-6518311-B2 | Analgesics | D-PHARM LTD. (IL) | 2003-02-11 | — | — | US | disclosed |
| WO-2003000173-A2 | USE OF BRANCHED-CHAIN FATTY ACIDS AND DERIVATIVES THEREOF FOR THE TREATMENT OF PAIN | D-PHARM LIMITED (IL) | 2003-01-03 | — | — | WO | disclosed |
| US-20020042445-A1 | Use of branched-chain fatty acids and derivatives thereof for the treatment of pain | D-PHARM LTD. (IL) | 2002-04-11 | — | — | US | disclosed |
| WO-2002011666-A2 | DERIVATIVES OF BRANCHED-CHAIN LIPOPHILIC MOLECULES AND USES THEREOF | D-PHARM LTD. (IL) | 2002-02-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135381-A1 | Derivatives of branch-chain lipophilic molecular and uses thereof | PLIN3, GLS, LIPG | CHRM1 4678/4885AKR1A1 2673/4885CHRM3 4216/4885 |
| US-20040235949-A1 | Use of branched-chain fatty acids and derivatives thereof for the treatment of pain | OPRL1, ELOVL5, ELOVL1 | CHRM1 1897/4885AKR1A1 539/4885CHRM3 927/4885 |
| US-20020042445-A1 | Use of branched-chain fatty acids and derivatives thereof for the treatment of pain | OPRL1, ELOVL5, ELOVL1 | CHRM1 1897/4885AKR1A1 539/4885CHRM3 927/4885 |
| US-20030186897-A1 | Derivatives of branched-chain lipophilic molecules and uses thereof | PLIN3, PLIN5, SLC27A1 | CHRM1 4778/4885AKR1A1 2053/4885CHRM3 4378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.