Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL68540 | 0.71 | MMP2 (0.54) | KMT2ALMNAGAAMEN1ALOX12 | |
| SCHEMBL11119770 | 0.70 | OPRM1 (0.36) | KMT2ALMNAGAAMEN1ALOX12 | |
| SCHEMBL267675 | 0.69 | ELANE (0.56) | KMT2ALMNAGAAMEN1ALOX12 | |
| SCHEMBL265915 | 0.67 | GAA (0.41) | KMT2ALMNAGAAMEN1ALOX12 | |
| SCHEMBL4412405 | 0.67 | GAA (0.50) | KMT2ALMNAGAAMEN1ALOX12 | |
| SCHEMBL8905488 | 0.67 | OPRM1 (0.38) | KMT2ALMNAGAAMEN1ALOX12 | |
| SCHEMBL8597730 | 0.67 | MMP2 (0.48) | KMT2ALMNAGAAMEN1ALOX12 | |
| SCHEMBL6811886 | 0.63 | HSD17B10 (0.44) | KMT2ALMNAGAAMEN1ALOX12 | |
| SCHEMBL27851038 | 0.62 | AKR1C1 (0.48) | — | |
| SCHEMBL6889612 | 0.62 | MEN1 (0.36) | KMT2AGAAMEN1ALOX12ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2150247-A1 | POLYETHYLENE GLYCOL ESTERS AND COSMETIC AND/OR DERMATOLOGICAL PREPARATIONS | Symrise GmbH & Co. KG (DE) | 2010-02-10 | — | — | EP | disclosed |
| WO-2008128892-A1 | POLYETHYLENE GLYCOL ESTERS AND COSMETIC AND/OR DERMATOLOGICAL PREPARATIONS | SYMRISE GMBH & CO. KG (DE) | 2008-10-30 | — | — | WO | disclosed |