Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | CTSE | P14091 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11119770 | 0.84 | OPRM1 (0.36) | OPRM1OPRD1OPRK1OPRL1LMNA | |
| SCHEMBL68540 | 0.69 | MMP2 (0.54) | LMNAMEN1GAAALOX12KMT2A | |
| SCHEMBL267675 | 0.68 | ELANE (0.56) | LMNAMEN1GAAALOX12KMT2A | |
| SCHEMBL265915 | 0.65 | GAA (0.41) | LMNAMEN1GAAALOX12KMT2A | |
| SCHEMBL4412405 | 0.65 | GAA (0.50) | LMNAMEN1GAAALOX12KMT2A | |
| SCHEMBL8597730 | 0.62 | MMP2 (0.48) | LMNAMEN1GAAALOX12KMT2A | |
| SCHEMBL31233809 | 0.59 | MMP9 (0.57) | MEN1KMT2APOLBTSHR | |
| SCHEMBL2051340 | 0.59 | PGR (0.39) | LMNAMEN1GAAALOX12KMT2A | |
| SCHEMBL107889 | 0.56 | HRH1 (0.56) | OPRM1OPRK1LMNAMEN1ALOX12 | |
| SCHEMBL432757 | 0.55 | AOC3 (0.46) | LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5604206-A | USEFUL FOR THE TREATMENT OF INFLAMMATION AND PAIN | MEDICE CHEM.-PHARM. FABRIK PUTTER GMBH & CO. KG (DE) | 1997-02-18 | — | — | US | disclosed |