Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | UBE2M | P61081 | 1/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2294293 | 0.81 | GRIN2B (0.50) | KMT2ASMN1; SMN2RAB9AGAAMAPT | |
| SCHEMBL2291227 | 0.79 | HPGDS (0.53) | KMT2ASMN1; SMN2POLBHPGDLMNA | |
| SCHEMBL2294464 | 0.77 | TRPV1 (0.44) | KMT2ASMN1; SMN2RAB9AGAAMAPT | |
| SCHEMBL2294335 | 0.77 | RAB9A (0.58) | KMT2ASMN1; SMN2RAB9AGAAMAPT | |
| SCHEMBL2292379 | 0.77 | TSHR (0.50) | KMT2ASMN1; SMN2GAAMAPTPOLB | |
| SCHEMBL2297093 | 0.76 | KMT2A (0.54) | KMT2ASMN1; SMN2RAB9AGAAMAPT | |
| SCHEMBL2289626 | 0.76 | TSHR (0.45) | KMT2ASMN1; SMN2RAB9AGAAMAPT | |
| SCHEMBL3640469 | 0.69 | RAB9A (0.55) | KMT2ASMN1; SMN2RAB9AGAAMAPT | |
| SCHEMBL2291074 | 0.69 | LMNA (0.53) | KMT2ASMN1; SMN2RAB9AGAAMAPT | |
| SCHEMBL2294071 | 0.69 | ALDH1A1 (0.51) | KMT2ASMN1; SMN2RAB9AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164326-A1 | AMIDE COMPOUNDS AND THE USE THEREOF | Euro-Celtique, S.A. (LU) | 2010-03-24 | — | — | EP | disclosed |
| WO-2008150447-A1 | AMIDE COMPOUNDS AND THE USE THEREOF | EURO-CELTIQUE S.A. (LU) | 2008-12-11 | — | — | WO | disclosed |