SCHEMBL3634599

SCHEMBL3634599

[c]1cc(-c2ccccc2)[c]c(-c2ccccc2)c1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
MAPK1 P28482 2/20 0.33
RAB9A P51151 2/20 0.33
NPC1 O15118 1/20 0.33
CYP1A2 P05177 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
CYP3A4 P08684 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
NOTUM Q6P988 1/20 0.32
MMP3 P08254 1/20 0.32
BCL2L1 Q07817 1/20 0.32
BACE1 P56817 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5182001 0.84 ALDH1A1 (0.33) ALDH1A1RAB9ANPC1LMNA
SCHEMBL5179353 0.84 ALDH1A1 (0.36) ALDH1A1MAPK1TDP1
SCHEMBL379055 0.77 ALDH1A1 (0.47) ALDH1A1MAPK1RAB9ANPC1CYP1A2
SCHEMBL195477 0.76 ALDH1A1 (0.53) ALDH1A1MAPK1RAB9ANPC1CYP1A2
SCHEMBL27385746 0.73 ALDH1A1 (0.50) ALDH1A1MAPK1RAB9ANPC1CYP1A2
SCHEMBL456946 0.72 ALDH1A1 (0.50) ALDH1A1MAPK1RAB9ANPC1CYP1A2
SCHEMBL608940 0.72 ALDH1A1 (0.36) ALDH1A1
SCHEMBL5047733 0.71 ALDH1A1 (0.47) ALDH1A1MAPK1RAB9ANPC1CYP1A2
SCHEMBL5873284 0.70 ALDH1A1 (0.47) ALDH1A1MAPK1RAB9ANPC1CYP1A2
SCHEMBL723026 0.70 ALDH1A1 (0.40) ALDH1A1MAPK1RAB9ANPC1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3649180-B1 POLYMERS COMPRISING SULFONATED 2,6-DIPHENYL- 1,4-PHENYLENE OXIDE REPEATING UNITS MXPOLYMERS B V (NL) 2023-09-27 EP claimed
CN-115010839-B Amine-containing bisphenol tetradentate ligand fourth subgroup metal complex catalyst system and application thereof 吉林大学 2023-06-20 CN claimed
EP-3778748-B1 NONHALOGEN FLAME RETARDANT RESIN COMPOSITION AND FLAME RETARDANT RESIN MOLDED ARTICLE MANUFACTURED THEREFROM LG CHEMICAL LTD (KR) 2023-04-26 EP claimed
EP-2739954-B1 GAS FLUX MEASUREMENT USING TRAPS UNIV COLORADO STATE RES FOUND (US) 2017-10-11 EP claimed
EP-2094775-B1 OPTICALLY TRANSPARENT, XRAY-OPAQUE COMPOSITION, METHODS OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME SABIC GLOBAL TECHNOLOGIES BV (NL) 2017-03-08 EP claimed
EP-2684025-B1 BREATH KETONE DETECTOR AKERS BIOSCIENCES INC (US) 2016-08-10 EP claimed
EP-2153217-A1 METHOD FOR DETERMINING THE SENSITIVE OR INSENSITIVE NATURE OF A HEXOGEN EURENCO (FR) 2010-02-17 EP claimed
EP-1651718-B1 FLAMEPROOF THERMOPLASTIC RESIN COMPOSITION CHEIL IND INC (KR) 2009-03-11 EP claimed
WO-2009001006-A1 METHOD FOR DETERMINING THE SENSITIVE OR INSENSITIVE NATURE OF A HEXOGEN EURENCO FRANCE (FR) 2008-12-31 WO claimed
EP-0920816-B1 Method of deodorising a tobacco smoke filter element BRITISH AMERICAN TOBACCO CO (GB) 2003-03-26 EP claimed
EP-0649607-B1 Improvements relating to tobacco smoke filter elements BRITISH AMERICAN TOBACCO CO (GB) 2000-12-27 EP claimed
EP-0618985-B1 POLYMERIC MONOFILAMENT AND FELT MADE THEREFROM ALLIED SIGNAL INC (US) 1996-09-04 EP claimed
EP-0052854-B1 POLYPHENYLENE OXIDE COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-07-02 EP claimed
CN-115820115-B Use of organosiloxanes with aromatic groups in barrier coatings 赢创运营有限公司 2024-05-07 CN disclosed
CN-115010839-B Amine-containing bisphenol tetradentate ligand fourth subgroup metal complex catalyst system and application thereof 吉林大学 2023-06-20 CN disclosed
EP-3729073-B1 METHOD OF DETECTING AN INSECT INFESTATION CENTRE SCIENT ET TECHNIQUE DU BATIMENT CSTB (FR) 2022-06-08 EP disclosed
WO-2003091293-A1 HIGH DIMENSION STABILITY AND HIGH PROCESSABILITY POLYETHYLENE IN INJECTION MOULDING ATOFINA RESEARCH (BE) 2003-11-06 WO disclosed
WO-2002102896-A1 STABILISED THERMOPLASTIC MOULDING COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2002-12-27 WO disclosed
EP-1080709-A2 Absorbent article KAO CORPORATION (JP) 2001-03-07 EP disclosed
EP-0534388-A1 Tungsten-imido catalysts for ring-opening metathesis polymerization of cycloolefins HERCULES INCORPORATED (US) 1993-03-31 EP disclosed