SCHEMBL5182001

SCHEMBL5182001

Cc1[c]c(-c2ccccc2)c[c]c1

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.31
LMNA P02545 1/20 0.31
TSHR P16473 1/20 0.31
ALOX12 P18054 1/20 0.31
ACHE P22303 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
NR1H2 P55055 1/20 0.31
NR1H3 Q13133 1/20 0.31
GRM6 O15303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3634599 0.84 ALDH1A1 (0.42) ALDH1A1LMNANPC1RAB9A
SCHEMBL5179353 0.74 ALDH1A1 (0.36) ALDH1A1
SCHEMBL1803708 0.73 ALDH1A1 (0.36) ALDH1A1L3MBTL1LMNATSHRALOX12
SCHEMBL195576 0.70 LMNA (0.36) ALDH1A1L3MBTL1LMNATSHRALOX12
SCHEMBL14635117 0.70 ALDH1A1 (0.39) ALDH1A1LMNANPC1RAB9A
SCHEMBL723358 0.68 ALDH1A1 (0.36) ALDH1A1L3MBTL1LMNATSHRALOX12
SCHEMBL195477 0.67 ALDH1A1 (0.53) ALDH1A1LMNANPC1RAB9A
SCHEMBL7914615 0.65 LMNA (0.41) ALDH1A1L3MBTL1LMNATSHRALOX12
SCHEMBL7707730 0.65 MAPT (0.40) ALDH1A1L3MBTL1LMNATSHRALOX12
SCHEMBL27385746 0.65 ALDH1A1 (0.50) ALDH1A1LMNANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4244286-B1 POLYBUTYLENE TEREPHTHALATE COMPOSITION AND RADAR DEVICE COMPONENT THEREOF BASF SE (DE) 2024-07-10 EP claimed
EP-1311612-B1 REACTOR ALLOY OF SYNDIOTACTIC POLYSTYRENE HAVING HIGH IMPACT RESISTANCE SAMSUNG ATOFINA CO LTD (KR) 2007-02-28 EP claimed
EP-0200185-B1 THERMOPLASTIC MOULDING MASS BASF Aktiengesellschaft (DE) 1988-11-30 EP disclosed