SCHEMBL456946

SCHEMBL456946

[c]1c(-c2ccccc2)cc(-c2ccccc2)cc1-c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
CRHBP P24387 2/20 0.41
CRHR2 Q13324 2/20 0.41
MAPK1 P28482 2/20 0.39
KDM4E B2RXH2 2/20 0.39
HTT P42858 2/20 0.39
NPC1 O15118 1/20 0.39
NTSR1 P30989 1/20 0.39
RAB9A P51151 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
UHRF1 Q96T88 1/20 0.39
MAOA P21397 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
NOTUM Q6P988 1/20 0.38
MMP3 P08254 1/20 0.38
BCL2L1 Q07817 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5873284 0.97 ALDH1A1 (0.47) ALDH1A1CRHBPCRHR2MAPK1KDM4E
SCHEMBL4647857 0.87 NPC1 (0.49) ALDH1A1KDM4ENPC1NTSR1RAB9A
SCHEMBL723026 0.86 ALDH1A1 (0.40) ALDH1A1CRHBPCRHR2MAPK1HTT
SCHEMBL28235453 0.84 CRHBP (0.43) ALDH1A1CRHBPCRHR2KDM4EHTT
SCHEMBL14635117 0.84 ALDH1A1 (0.39) ALDH1A1CRHBPCRHR2MAPK1KDM4E
SCHEMBL7950746 0.83 ALDH1A1 (0.35) ALDH1A1CRHBPCRHR2MAPK1KDM4E
SCHEMBL5873304 0.82 KIF11 (0.44) ALOX5CYP19A1
SCHEMBL7914615 0.79 LMNA (0.41) ALDH1A1KDM4EHTTNPC1RAB9A
SCHEMBL3822038 0.79 ALDH1A1 (0.38) ALDH1A1KDM4EMAOACYP1A2TAAR1
SCHEMBL6761031 0.77 MEN1 (0.46) ALDH1A1MAPK1KDM4EHTTMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 400 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118344695-A Hydroxyl-enriched cycloolefin copolymer long afterglow material and application thereof 重庆理工大学 2024-07-16 CN claimed
CN-111408411-B Catalyst composition, preparation method thereof and application thereof in reaction of synthesizing 1-butene by ethylene selective dimerization 中国石油化工股份有限公司 2024-02-13 CN claimed
CN-112424122-B Partially hydrogenated chlorosilanes and process for preparing same by selective hydrogenation 赢创运营有限公司 2024-02-02 CN claimed
US-11827522-B2 Partially hydrogenated chlorosilanes and methods for preparing same by selective hydrogenation EVONIK OPERATIONS GMBH (DE) 2023-11-28 US claimed
CN-111408412-B Catalyst composition, preparation method thereof and application thereof in reaction of synthesizing 1-butene by ethylene selective dimerization 中国石油化工股份有限公司 2023-05-09 CN claimed
CN-111408405-B Catalyst composition, preparation method thereof and application thereof in reaction for synthesizing 1-butene through selective dimerization of ethylene 中国石油化工股份有限公司 2023-03-28 CN claimed
CN-114989519-A Application of cycloolefin polymer in long afterglow material 重庆理工大学 2022-09-02 CN claimed
CN-112694376-B Kinetic resolution method of allyl tertiary alcohol catalyzed by chiral phosphoric acid 浙江工业大学 2022-06-17 CN claimed
US-11276825-B2 Organic molecules for use in organic devices CYNORA GMBH (DE) 2022-03-15 US claimed
EP-3569606-B1 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO (1,2-F)PHENANTHRIDINE AND DIIMIDAZO (1,2-A; 1', 2'-C)QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF UNIVERSAL DISPLAY CORP (US) 2022-01-05 EP claimed
US-20070243390-A1 Bivalent monomeric phenoxy tin catalysts E. I. DU PONT DE NEMOURS AND COMPANY 2007-10-18 US claimed
WO-2007095118-A2 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO[1,2-f]PHENANTHRIDINE AND DIIMIDAZO[1,2-A:1',2'-C]QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF UNIVERSAL DISPLAY CORPORATION (US) 2007-08-23 WO claimed
US-20070190359-A1 Metal complexes of cyclometallated imidazo[1,2-ƒ]phenanthridine and diimidazo[1,2-a:1',2'-c]quinazoline ligands and isoelectronic and benzannulated analogs thereof UNIVERSAL DISPLAY CORPORATION 2007-08-16 US claimed
US-20030228978-A1 Catalysts containing per-ortho aryl substituted aryl or heteroaryl substituted nitrogen donors EASTMAN CHEMICAL COMPANY 2003-12-11 US claimed
US-6579823-B2 Group 8-10 metal complex comprising a bidentate or variable denticity ligand; polymerization of olefins EASTMAN CHEMICAL COMPANY 2003-06-17 US claimed
EP-1317490-A1 CATALYSTS CONTAINING PER-ORTHO ARYL SUBSTITUTED ARYL OR HETEROARYL SUBSTITUTED NITROGEN DONORS EASTMAN CHEMICAL COMPANY (US) 2003-06-11 EP claimed
US-20020049135-A1 Catalysts containing per-ortho aryl substituted aryl or heteroaryl substituted nitrogen donors E. I. DU PONT DE NEMOURS AND COMPANY 2002-04-25 US claimed
WO-2002022694-A1 CATALYSTS CONTAINING PER-ORTHO ARYL SUBSTITUTED ARYL OR HETEROARYL SUBSTITUTED NITROGEN DONORS EASTMAN CHEMICAL COMPANY (US) 2002-03-21 WO claimed
US-6333292-B1 AS POLYMERIZATION CATALYST IN ADDITION POLYMERIZATION BP CHEMICALS LIMITED (GB) 2001-12-25 US claimed
EP-0953571-A1 Catalysts for olefin polymerisation BP Chemicals Limited (GB) 1999-11-03 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070243390-A1 Bivalent monomeric phenoxy tin catalysts BMI1, TELO2, PCNA ALDH1A1 4078/4885CRHBP 3806/4885CRHR2 2923/4885
US-11276825-B2 Organic molecules for use in organic devices AOX1, OR10J3, L1CAM ALDH1A1 11/4885CRHBP 4328/4885CRHR2 2925/4885
US-20030228978-A1 Catalysts containing per-ortho aryl substituted aryl or heteroaryl substituted nitrogen donors NOX3, AOC3, AHR ALDH1A1 3336/4885CRHBP 3734/4885CRHR2 4344/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.