Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456946 | 0.97 | ALDH1A1 (0.50) | ALDH1A1MAPK1TAAR1HSD17B10CYP1A2 | |
| SCHEMBL4647857 | 0.89 | NPC1 (0.49) | ALDH1A1TDP1ALOX5KDM4ENPC1 | |
| SCHEMBL723026 | 0.84 | ALDH1A1 (0.40) | ALDH1A1MAPK1TAAR1HSD17B10CYP1A2 | |
| SCHEMBL5873304 | 0.84 | KIF11 (0.44) | ALOX5KIF11DHODH | |
| SCHEMBL28235453 | 0.81 | CRHBP (0.43) | ALDH1A1HSD17B10CYP1A2MMP3BCL2L1 | |
| SCHEMBL14635117 | 0.81 | ALDH1A1 (0.39) | ALDH1A1MAPK1CRHBPCRHR2KDM4E | |
| SCHEMBL7950746 | 0.81 | ALDH1A1 (0.35) | ALDH1A1MAPK1CRHBPCRHR2KDM4E | |
| SCHEMBL6761031 | 0.80 | MEN1 (0.46) | ALDH1A1MAPK1TAAR1HSD17B10CYP1A2 | |
| SCHEMBL3819329 | 0.78 | RXRA (0.42) | ALDH1A1TAAR1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL3822038 | 0.77 | ALDH1A1 (0.38) | ALDH1A1TAAR1CYP1A2TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7056996-B2 | Productivity catalysts and microstructure control | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-06-06 | — | — | US | disclosed |
| US-20040127658-A1 | Productivity catalysts and microstructure control | EASTMAN CHEMICAL COMPANY | 2004-07-01 | — | — | US | disclosed |
| US-20040077809-A1 | Productivity catalysts and microstructure control | EASTMAN CHEMICAL COMPANY | 2004-04-22 | — | — | US | disclosed |
| EP-1404723-A2 | OLEFIN POLYMERIZATION PROCESSES USING SUPPORTED CATALYSTS | EASTMAN CHEMICAL COMPANY (US) | 2004-04-07 | — | — | EP | disclosed |
| EP-1351997-A2 | IMPROVED PRODUCTIVITY CATALYSTS AND MICROSTRUCTURE CONTROL | EASTMAN CHEMICAL COMPANY (US) | 2003-10-15 | — | — | EP | disclosed |
| US-6605677-B2 | Group 8-10 transition metal based supported catalyst where the support is treated with a pore-filling agent; improved the catalyst productivity in the presence of hydrogen | EASTMAN CHEMICAL COMPANY | 2003-08-12 | — | — | US | disclosed |
| US-20020091210-A1 | Olefin polymerization processes using supported catalysts | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-07-11 | — | — | US | disclosed |
| US-20020065192-A1 | Productivity catalysts and microstructure control | MACKENZIE PETER BORDEN (US) | 2002-05-30 | — | — | US | disclosed |
| WO-2002036641-A2 | IMPROVED PRODUCTIVITY CATALYSTS AND MICROSTRUCTURE CONTROL | EASTMAN CHEMICAL COMPANY (US) | 2002-05-10 | — | — | WO | disclosed |
| WO-2002036642-A2 | OLEFIN POLYMERIZATION PROCESSES USING SUPPORTED CATALYSTS | EASTMAN CHEMICAL COMPANY (US) | 2002-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077809-A1 | Productivity catalysts and microstructure control | MYB, ST3GAL3, FASN | ALDH1A1 3431/4885MAPK1 2128/4885TAAR1 1911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.