Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30422223 | 1.00 | ALOX5 (0.43) | ALOX5ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL1615170 | 0.87 | MAOB (0.51) | ALOX5ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL3886209 | 0.79 | IDO1 (0.47) | ALOX5ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL22311238 | 0.79 | PLK4 (0.43) | MAPTKDM4EMEN1KMT2AGPR3 | |
| SCHEMBL21862373 | 0.79 | MAPT (0.40) | MAPTKDM4EMEN1KMT2AGPR3 | |
| SCHEMBL8413396 | 0.77 | MAOA (0.51) | ALOX5ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL24343669 | 0.76 | MAPK1 (0.45) | ALOX5ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL23168590 | 0.76 | CYP2A6 (0.38) | ALOX5MAPTMEN1KMT2AGPR3 | |
| SCHEMBL5218956 | 0.75 | MAOA (0.57) | ALOX5ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL13311458 | 0.75 | ALDH1A1 (0.41) | ALOX5ALDH1A1MAPTKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11851423-B2 | Heterocyclic compound and organic light emitting device comprising the same | LG CHEM, LTD. (KR) | 2023-12-26 | — | — | US | disclosed |
| US-20200039971-A1 | NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME | LG CHEM, LTD. (KR) | 2020-02-06 | — | — | US | disclosed |
| US-20200039971-A1 | NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME | LG CHEM, LTD. (KR) | 2020-02-06 | — | — | US | disclosed |
| EP-2176254-A1 | DNA PK INHIBITORS | Kudos Pharmaceuticals Limited (GB) | 2010-04-21 | — | — | EP | disclosed |
| US-20090042865-A1 | DNA-PK INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2009-02-12 | — | — | US | disclosed |
| US-20090042865-A1 | DNA-PK INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2009-02-12 | — | — | US | disclosed |
| US-20090042865-A1 | DNA-PK INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2009-02-12 | — | — | US | disclosed |
| WO-2009010761-A1 | DNA PK INHIBITORS | KUDOS PHARMACEUTICALS LIMITED (GB) | 2009-01-22 | — | — | WO | disclosed |
| WO-2009010761-A1 | DNA PK INHIBITORS | KUDOS PHARMACEUTICALS LIMITED (GB) | 2009-01-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042865-A1 | DNA-PK INHIBITORS | DNA2, PKN2, TOP1 | ALOX5 4618/4885ALDH1A1 3995/4885MAPT 4759/4885 |
| US-20200039971-A1 | NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME | CRY1, CRY2, CYP1A1 | ALOX5 1016/4885ALDH1A1 39/4885MAPT 961/4885 |
| US-11851423-B2 | Heterocyclic compound and organic light emitting device comprising the same | CRY1, CYP1A1, CRY2 | ALOX5 797/4885ALDH1A1 39/4885MAPT 992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.