Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 4/20 | 0.48 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SCN1A | P35498 | 2/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.48 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.48 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.48 |
| ▸ | GBA1 | P04062 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3648377 | 0.82 | SCN4A (0.61) | SCN4ASCN5ALMNASCN1ASCN9A | |
| SCHEMBL11691799 | 0.80 | ALDH1A1 (0.41) | SCN4ALMNATSHRALDH1A1THRA | |
| SCHEMBL680993 | 0.80 | TSHR (0.48) | LMNATSHRCYP3A4ALDH1A1THRA | |
| SCHEMBL28590846 | 0.80 | SCN4A (0.63) | SCN4ASCN5ALMNASCN1ASCN9A | |
| SCHEMBL28590843 | 0.80 | SCN4A (0.63) | SCN4ASCN5ALMNASCN1ASCN9A | |
| SCHEMBL19866541 | 0.78 | THRB (0.44) | SCN4ATSHRALDH1A1THRATHRB | |
| SCHEMBL2883398 | 0.77 | ALDH1A1 (0.44) | TSHRCYP3A4ALDH1A1THRATHRB | |
| SCHEMBL10192340 | 0.77 | ALDH1A1 (0.44) | TSHRCYP3A4ALDH1A1THRATHRB | |
| SCHEMBL5478851 | 0.75 | TSHR (0.58) | LMNATSHRCYP3A4ALDH1A1THRA | |
| SCHEMBL676691 | 0.73 | TSHR (0.52) | LMNATSHRALDH1A1THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8324263-B2 | Microbiocidally active carboxamides | SYNGENTA CROP PROTECTION, LLC (US) | 2012-12-04 | — | — | US | disclosed |
| US-8324263-B2 | Microbiocidally active carboxamides | SYNGENTA CROP PROTECTION, LLC (US) | 2012-12-04 | — | — | US | disclosed |
| US-8324263-B2 | Microbiocidally active carboxamides | SYNGENTA CROP PROTECTION, LLC (US) | 2012-12-04 | — | — | US | disclosed |
| US-20100292239-A1 | NOVEL MICROBIOCIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-11-18 | — | — | US | disclosed |
| US-20100292239-A1 | NOVEL MICROBIOCIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-11-18 | — | — | US | disclosed |
| US-20100292239-A1 | NOVEL MICROBIOCIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-11-18 | — | — | US | disclosed |
| EP-2181097-A1 | NOVEL MICROBIOCIDES | Syngeta Participations AG (CH) | 2010-05-05 | — | — | EP | disclosed |
| WO-2009012998-A1 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-01-29 | — | — | WO | disclosed |
| WO-2009012998-A1 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-01-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292239-A1 | NOVEL MICROBIOCIDES | CD14, FPR1, MPO | SCN4A 4199/4885SCN5A 3982/4885LMNA 4162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.