Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | SI | P14410 | 3/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PNP | P00491 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL363191 | 0.90 | ALDH1A1 (0.38) | ALDH1A1MAPTMEN1KMT2ABRD4 | |
| SCHEMBL363804 | 0.83 | MGAM (0.38) | MAPTMEN1KMT2ABRD4MGAM | |
| SCHEMBL1390327 | 0.80 | CREBBP (0.42) | ALDH1A1MAPTMEN1KMT2ABRD4 | |
| SCHEMBL362297 | 0.75 | MGAM (0.38) | BRD4MGAMGAASIMGAM2 | |
| SCHEMBL364331 | 0.75 | MGAM (0.43) | MEN1KMT2ABRD4MGAMGAA | |
| SCHEMBL365670 | 0.73 | L3MBTL1 (0.40) | ALDH1A1MAPTBRD4MGAMGAA | |
| SCHEMBL12505663 | 0.73 | MGAM (0.41) | KMT2ABRD4MGAMGAASI | |
| SCHEMBL370270 | 0.72 | POLB (0.38) | ALDH1A1MAPTMEN1KMT2AMGAM | |
| SCHEMBL368192 | 0.72 | CREBBP (0.40) | ALDH1A1MAPTMEN1KMT2ABRD4 | |
| SCHEMBL368193 | 0.72 | CREBBP (0.40) | ALDH1A1MAPTMEN1KMT2ABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |