Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 3/20 | 0.39 |
| ▸ | FNTB | P49356 | 3/20 | 0.39 |
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.38 |
| ▸ | BAZ2A | Q9UIF9 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SELL | P14151 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SELP | P16109 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367221 | 0.92 | BAZ2B (0.42) | PTGS2FNTAFNTBBAZ2BBAZ2A | |
| SCHEMBL366820 | 0.90 | IDO1 (0.43) | PTGS2FNTAFNTBBAZ2BBAZ2A | |
| SCHEMBL367255 | 0.89 | PTGS2 (0.42) | PTGS2FNTAFNTBDHODHBAZ2B | |
| SCHEMBL365770 | 0.88 | BAZ2B (0.45) | BAZ2BBAZ2AKDM4EALDH1A1TP53 | |
| SCHEMBL364537 | 0.85 | BAZ2B (0.38) | BAZ2BBAZ2AKDM4EALDH1A1MAPT | |
| SCHEMBL365272 | 0.82 | CA12 (0.42) | PTGS2FNTAFNTBBAZ2BBAZ2A | |
| SCHEMBL365788 | 0.81 | BAZ2B (0.45) | PTGS2FNTAFNTBBAZ2BBAZ2A | |
| SCHEMBL365406 | 0.78 | STS (0.39) | KDM4ECA12ALDH1A1CA1CA2 | |
| SCHEMBL366789 | 0.78 | IDO1 (0.38) | PTGS2FNTAFNTBBAZ2BBAZ2A | |
| SCHEMBL365258 | 0.78 | KDM4E (0.42) | PTGS2FNTAFNTBBAZ2BBAZ2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |