Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.40 |
| ▸ | BAZ2A | Q9UIF9 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 3/20 | 0.39 |
| ▸ | FNTB | P49356 | 3/20 | 0.39 |
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367221 | 0.92 | BAZ2B (0.42) | PTGS2BAZ2BBAZ2AFNTAFNTB | |
| SCHEMBL366820 | 0.90 | IDO1 (0.43) | PTGS2BAZ2BBAZ2AIDO1FNTA | |
| SCHEMBL365022 | 0.89 | PTGS2 (0.39) | PTGS2BAZ2BBAZ2AIDO1FNTA | |
| SCHEMBL365788 | 0.86 | BAZ2B (0.45) | PTGS2BAZ2BBAZ2AIDO1FNTA | |
| SCHEMBL366789 | 0.83 | IDO1 (0.38) | PTGS2BAZ2BBAZ2AIDO1FNTA | |
| SCHEMBL365770 | 0.83 | BAZ2B (0.45) | BAZ2BBAZ2AMAPT | |
| SCHEMBL367749 | 0.82 | NPC1 (0.41) | PTGS2BAZ2BBAZ2AFNTAFNTB | |
| SCHEMBL364537 | 0.80 | BAZ2B (0.38) | BAZ2BBAZ2AMAPT | |
| SCHEMBL366810 | 0.79 | PTGS2 (0.45) | PTGS2BAZ2BBAZ2AIDO1FNTA | |
| SCHEMBL366115 | 0.78 | CA1 (0.41) | PTGS2IDO1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |