Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 3/20 | 0.38 |
| ▸ | BAZ2A | Q9UIF9 | 3/20 | 0.38 |
| ▸ | ERN1 | O75460 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | PMM2 | O15305 | 1/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | G6PD | P11413 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366789 | 0.89 | IDO1 (0.38) | BAZ2BBAZ2AERN1EGFRSRC | |
| SCHEMBL367221 | 0.87 | BAZ2B (0.42) | BAZ2BBAZ2AKDM4EALDH1A1MAPT | |
| SCHEMBL365770 | 0.86 | BAZ2B (0.45) | BAZ2BBAZ2AKDM4EMEN1APAF1 | |
| SCHEMBL366817 | 0.85 | NPC1 (0.39) | BAZ2BBAZ2AERN1KDM4EALDH1A1 | |
| SCHEMBL365022 | 0.85 | PTGS2 (0.39) | BAZ2BBAZ2AKDM4EALDH1A1MAPT | |
| SCHEMBL365916 | 0.82 | KDM4E (0.40) | BAZ2BBAZ2AERN1EGFRSRC | |
| SCHEMBL365255 | 0.80 | RAB9A (0.37) | BAZ2BBAZ2AKDM4EMEN1APAF1 | |
| SCHEMBL367255 | 0.80 | PTGS2 (0.42) | BAZ2BBAZ2AMAPT | |
| SCHEMBL366820 | 0.75 | IDO1 (0.43) | BAZ2BBAZ2AKDM4EALDH1A1MAPT | |
| SCHEMBL365788 | 0.74 | BAZ2B (0.45) | BAZ2BBAZ2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |