Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 3/20 | 0.42 |
| ▸ | BAZ2A | Q9UIF9 | 3/20 | 0.42 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365022 | 0.92 | PTGS2 (0.39) | BAZ2BBAZ2APTGS2HSD17B10KDM4E | |
| SCHEMBL367255 | 0.92 | PTGS2 (0.42) | BAZ2BBAZ2APARP1PTGS2HSD17B10 | |
| SCHEMBL365770 | 0.91 | BAZ2B (0.45) | BAZ2BBAZ2AKDM4EBRD4ALDH1A1 | |
| SCHEMBL364537 | 0.87 | BAZ2B (0.38) | BAZ2BBAZ2AKDM4EALDH1A1MAPT | |
| SCHEMBL367765 | 0.81 | NPC1 (0.43) | BAZ2BBAZ2APARP1KDM4EALDH1A1 | |
| SCHEMBL366820 | 0.81 | IDO1 (0.43) | BAZ2BBAZ2APTGS2HSD17B10KDM4E | |
| SCHEMBL365406 | 0.80 | STS (0.39) | KDM4EALDH1A1MAPT | |
| SCHEMBL365788 | 0.78 | BAZ2B (0.45) | BAZ2BBAZ2APTGS2KDM4EBRD4 | |
| SCHEMBL367763 | 0.78 | BAZ2B (0.45) | BAZ2BBAZ2APARP1PTGS2HSD17B10 | |
| SCHEMBL365255 | 0.76 | RAB9A (0.37) | BAZ2BBAZ2AKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |