Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 10/20 | 0.45 |
| ▸ | BAZ2A | Q9UIF9 | 10/20 | 0.45 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.36 |
| ▸ | BRD2 | P25440 | 1/20 | 0.36 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.34 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367221 | 0.91 | BAZ2B (0.42) | BAZ2BBAZ2ABRD4MAPTKDM4E | |
| SCHEMBL365022 | 0.88 | PTGS2 (0.39) | BAZ2BBAZ2AMAPTKDM4EALDH1A1 | |
| SCHEMBL365788 | 0.88 | BAZ2B (0.45) | BAZ2BBAZ2ABRD4BRD9BRD2 | |
| SCHEMBL364537 | 0.86 | BAZ2B (0.38) | BAZ2BBAZ2AMAPTKDM4EMEN1 | |
| SCHEMBL365020 | 0.84 | BAZ2B (0.43) | BAZ2BBAZ2AMAPTKDM4EALDH1A1 | |
| SCHEMBL367255 | 0.83 | PTGS2 (0.42) | BAZ2BBAZ2AMAPT | |
| SCHEMBL367329 | 0.78 | BAZ2B (0.47) | BAZ2BBAZ2ABRD4BRD9MAPT | |
| SCHEMBL366820 | 0.78 | IDO1 (0.43) | BAZ2BBAZ2AMAPTKDM4EALDH1A1 | |
| SCHEMBL365406 | 0.77 | STS (0.39) | MAPTKDM4EMEN1APAF1ALDH1A1 | |
| SCHEMBL365255 | 0.76 | RAB9A (0.37) | BAZ2BBAZ2AMAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |