SCHEMBL3650249

SCHEMBL3650249

CCCCN(CCCC)CC(N)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G1B P04054 1/20 0.42
PLA2G2A P14555 1/20 0.42
KDM4E B2RXH2 3/20 0.41
MAPK1 P28482 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
CA12 O43570 2/20 0.37
CA1 P00915 2/20 0.37
CA9 Q16790 2/20 0.37
SPHK1 Q9NYA1 2/20 0.35
MAPT P10636 2/20 0.35
MMP1 P03956 1/20 0.34
MMP2 P08253 1/20 0.34
MMP3 P08254 1/20 0.34
MMP8 P22894 1/20 0.34
CYP2D6 P10635 2/20 0.33
POLB P06746 2/20 0.33
GMNN O75496 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27681607 0.80 KDM4E (0.43) PLA2G1BPLA2G2AKDM4EMAPK1TDP1
SCHEMBL29966470 0.80 KDM4E (0.51) PLA2G1BPLA2G2AKDM4EMAPK1TDP1
SCHEMBL9407962 0.79 PLA2G1B (0.41) PLA2G1BPLA2G2AKDM4EMAPK1TDP1
SCHEMBL5699103 0.79 GGPS1 (0.44) PLA2G1BPLA2G2AKDM4ESPHK1MAPT
SCHEMBL1009972 0.78 KDM4E (0.42) PLA2G1BPLA2G2AKDM4EMAPK1TDP1
SCHEMBL5435145 0.78 OPRM1 (0.44) PLA2G1BPLA2G2AKDM4EMAPK1TDP1
SCHEMBL7356304 0.77 KDM4E (0.46) PLA2G1BPLA2G2AKDM4EMAPK1TDP1
SCHEMBL474323 0.76 KDM4E (0.49) PLA2G1BPLA2G2AKDM4EMAPK1TDP1
SCHEMBL18567086 0.76 KDM4E (0.49) PLA2G1BPLA2G2AKDM4EMAPK1TDP1
SCHEMBL3679636 0.74 KDM4E (0.47) KDM4EMAPK1TDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10799610-B2 Cement products and methods of making and using the same PIONEER SURGICAL TECHNOLOGY, INC. (US) 2020-10-13 US disclosed
US-10413632-B2 Cement products and methods of making and using the same PIONEER SURGICAL TECHNOLOGY, INC. (US) 2019-09-17 US disclosed
US-20180264165-A1 CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME MIDCAP FINANCIAL TRUST 2018-09-20 US disclosed
US-9993576-B2 Cement products and methods of making and using the same PIONEER SURGICAL TECHNOLOGY, INC. (US) 2018-06-12 US disclosed
EP-2192886-B1 CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME PIONEER SURGICAL TECH INC (US) 2017-12-20 EP disclosed
US-20170333594-A1 CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME MIDCAP FINANCIAL TRUST 2017-11-23 US disclosed
US-9757493-B2 Cement products and methods of making and using the same PIONEER SURGICAL TECHNOLOGY, INC. (US) 2017-09-12 US disclosed
US-20160250376-A1 CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME TUTOGEN MEDICAL, INC. 2016-09-01 US disclosed
US-9358319-B2 Cement products and methods of making and using the same PIONEER SURGICAL TECHNOLOGY, INC. (US) 2016-06-07 US disclosed
EP-2877540-B1 CURABLE ANTIFOULING COMPOSITION, METHOD OF USE, AND ARTICLES 3M INNOVATIVE PROPERTIES CO (US) 2016-06-01 EP disclosed
US-20090270527-A1 CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME ANGSTROM MEDICA (US) 2009-10-29 US disclosed
WO-2009029734-A2 CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME PIONEER SURGICAL TECHNOLOGY, INC. (US) 2009-03-05 WO disclosed
US-7060352-B2 Method of detackifying an edge face of a roll of tape using a radiation curable composition 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-06-13 US disclosed
EP-1373423-B1 METHOD OF DETACKIFYING AN EDGE FACE OF A ROLL OF TAPE USING A RADIATION CURABLE COMPOSITION 3M INNOVATIVE PROPERTIES CO (US) 2006-03-29 EP disclosed
CN-1247721-C Method of detackifying an edge face of a roll of tape using a radiation curable composition 3M INNOVATIVE PROPERTIES CO (US) 2006-03-29 CN disclosed
CN-1492915-A Method for detackifying an edge face of a roll of tape using a radiation curable composition 3M 2004-04-28 CN disclosed
EP-1373423-A1 METHOD OF DETACKIFYING AN EDGE FACE OF A ROLL OF TAPE USING A RADIATION CURABLE COMPOSITION 3M Innovative Properties Company (US) 2004-01-02 EP disclosed
US-20020168514-A1 Method of detackifying an edge face of a roll of tape using a radiation curable composition 3M INNOVATIVE PROPERTIES COMPANY 2002-11-14 US disclosed
WO-2002074875-A1 METHOD OF DETACKIFYING AN EDGE FACE OF A ROLL OF TAPE USING A RADIATION CURABLE COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-09-26 WO disclosed
US-4332733-A CATALYTIC ISOMERIZATION OF DIELS-ALDER MALEIC ANHYDRIDE PRODUCTS MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1982-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180264165-A1 CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME BHMT2, SHMT1, BHMT PLA2G1B 3464/4885PLA2G2A 2882/4885KDM4E 211/4885
US-20160250376-A1 CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME BHMT2, SHMT1, BHMT PLA2G1B 3464/4885PLA2G2A 2882/4885KDM4E 211/4885
US-20170333594-A1 CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME BHMT2, SHMT1, BHMT PLA2G1B 3464/4885PLA2G2A 2882/4885KDM4E 211/4885
US-10799610-B2 Cement products and methods of making and using the same BHMT2, SHMT1, BHMT PLA2G1B 3464/4885PLA2G2A 2882/4885KDM4E 211/4885
US-10413632-B2 Cement products and methods of making and using the same BHMT2, SHMT1, BHMT PLA2G1B 3464/4885PLA2G2A 2882/4885KDM4E 211/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.