Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 3/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.34 |
| ▸ | KDM5A | P29375 | 4/20 | 0.34 |
| ▸ | KDM4A | O75164 | 2/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL187965 | 0.86 | — | — | |
| SCHEMBL930127 | 0.82 | CHRM2 (0.46) | GGPS1 | |
| SCHEMBL17933337 | 0.81 | GGPS1 (0.47) | GGPS1S1PR2S1PR1S1PR3S1PR5 | |
| SCHEMBL5885252 | 0.79 | GGPS1 (0.46) | GGPS1SPHK1S1PR2S1PR1S1PR3 | |
| SCHEMBL18612600 | 0.79 | GGPS1 (0.46) | GGPS1SPHK1S1PR2S1PR1S1PR3 | |
| SCHEMBL3650249 | 0.79 | PLA2G1B (0.42) | PLA2G1BPLA2G2ASPHK1CYP2D6GMNN | |
| SCHEMBL20993769 | 0.77 | AOC3 (0.34) | — | |
| SCHEMBL28661962 | 0.76 | — | — | |
| SCHEMBL4227388 | 0.76 | GGPS1 (0.43) | GGPS1S1PR2S1PR1S1PR3S1PR5 | |
| SCHEMBL5698971 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1507511-B1 | PERSONAL CARE COMPOSITIONS WITH HYDROXY AMINE NEUTRALIZED POLYMERS | UNILEVER PLC (GB) | 2006-07-26 | — | — | EP | disclosed |
| EP-1507511-A1 | PERSONAL CARE COMPOSITIONS WITH HYDROXY AMINE NEUTRALIZED POLYMERS | UNILEVER PLC (GB) | 2005-02-23 | — | — | EP | disclosed |
| EP-1507512-A1 | COSMETIC COMPOSITIONS WITH HYDROXY AMINE SALTS OF MALONIC ACID | UNILEVER PLC (GB) | 2005-02-23 | — | — | EP | disclosed |
| US-20040241131-A1 | Compositions containing malonate salts in preventing in-grown hair arising from shaving | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2004-12-02 | — | — | US | disclosed |
| US-20030228337-A1 | Personal care compositions with hydroxy amine neutralized polymers | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2003-12-11 | — | — | US | disclosed |
| WO-2003099253-A1 | PERSONAL CARE COMPOSITIONS WITH HYDROXY AMINE NEUTRALIZED POLYMERS | UNILEVER PLC (GB) | 2003-12-04 | — | — | WO | disclosed |
| WO-2003099252-A1 | COSMETIC COMPOSITIONS WITH HYDROXY AMINE SALTS OF MALONIC ACID | UNILEVER PLC (GB) | 2003-12-04 | — | — | WO | disclosed |
| US-20030224023-A1 | Cosmetic compositions with hydroxy amine salts of malonic acid | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2003-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030224023-A1 | Cosmetic compositions with hydroxy amine salts of malonic acid | CUTA, TYR, DDC | GGPS1 3654/4885PLA2G1B 2981/4885PLA2G2A 1956/4885 |
| US-20030228337-A1 | Personal care compositions with hydroxy amine neutralized polymers | CUTA, PARN, POLH | GGPS1 4626/4885PLA2G1B 2561/4885PLA2G2A 2714/4885 |
| US-20040241131-A1 | Compositions containing malonate salts in preventing in-grown hair arising from shaving | DPM1, POLR1C, MSH6 | GGPS1 1430/4885PLA2G1B 4033/4885PLA2G2A 3773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.