Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366625 | 0.93 | NCEH1 (0.32) | NCEH1KMT2ASMN1; SMN2 | |
| SCHEMBL366612 | 0.83 | ACHE (0.38) | NCEH1KMT2ASMN1; SMN2 | |
| SCHEMBL365084 | 0.82 | KDM4E (0.32) | KMT2A | |
| SCHEMBL366374 | 0.81 | ALDH1A1 (0.38) | KMT2A | |
| SCHEMBL365925 | 0.79 | ACHE (0.42) | — | |
| SCHEMBL365915 | 0.78 | S1PR3 (0.37) | KMT2ASMN1; SMN2 | |
| SCHEMBL366626 | 0.77 | KDM4E (0.32) | KMT2A | |
| SCHEMBL365490 | 0.77 | NCEH1 (0.39) | NCEH1KMT2ASMN1; SMN2 | |
| SCHEMBL365216 | 0.77 | ACHE (0.36) | KMT2APLA2G1B | |
| SCHEMBL365189 | 0.76 | ACHE (0.37) | NCEH1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |