Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367734 | 0.90 | ATM (0.40) | NCEH1KMT2AMEN1RAB9APKM | |
| SCHEMBL365256 | 0.87 | EGFR (0.40) | NCEH1KMT2AMEN1EGFRSRC | |
| SCHEMBL366612 | 0.84 | ACHE (0.38) | NCEH1KMT2ASMN1; SMN2 | |
| SCHEMBL365837 | 0.82 | CNR2 (0.37) | KMT2AMEN1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL366374 | 0.81 | ALDH1A1 (0.38) | KMT2AMEN1 | |
| SCHEMBL366481 | 0.81 | ACHE (0.39) | SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL367766 | 0.80 | L3MBTL1 (0.43) | KMT2AEGFRSRCSMN1; SMN2RAB9A | |
| SCHEMBL365192 | 0.80 | EGFR (0.41) | KMT2AMEN1EGFRSRCSMN1; SMN2 | |
| SCHEMBL367237 | 0.80 | TSHR (0.49) | KMT2AMEN1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL367225 | 0.80 | KMT2A (0.40) | KMT2AMEN1EGFRSRCSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |