Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.33 |
| ▸ | PLA2G2E | Q9NZK7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365006 | 0.93 | LTB4R (0.35) | ACHECYP11B1CYP11B2SIGMAR1SCN9A | |
| SCHEMBL366612 | 0.91 | ACHE (0.38) | ACHECYP11B1CYP11B2SIGMAR1SCN9A | |
| SCHEMBL366531 | 0.85 | MEN1 (0.36) | ACHECYP11B1CYP11B2SCN9AKDM4E | |
| SCHEMBL366374 | 0.84 | ALDH1A1 (0.38) | ACHESIGMAR1MAPTMEN1KMT2A | |
| SCHEMBL365189 | 0.84 | ACHE (0.37) | ACHECYP11B1CYP11B2SIGMAR1SCN9A | |
| SCHEMBL365915 | 0.82 | S1PR3 (0.37) | ACHES1PR3MAPTKMT2ANPC1 | |
| SCHEMBL365925 | 0.82 | ACHE (0.42) | ACHE | |
| SCHEMBL365215 | 0.78 | ACHE (0.36) | ACHECYP11B1CYP11B2SIGMAR1SCN9A | |
| SCHEMBL366851 | 0.78 | ALDH1A1 (0.38) | SIGMAR1S1PR3KDM4EMAPTMEN1 | |
| SCHEMBL365083 | 0.77 | NCEH1 (0.32) | PLA2G1BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |