Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 5/20 | 0.45 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | TPMT | P51580 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366559 | 0.94 | ATM (0.47) | ATMPLA2G4AL3MBTL1KDM4EMAPT | |
| SCHEMBL367750 | 0.91 | ATM (0.43) | ATMPLA2G4AL3MBTL1KDM4EMAPT | |
| SCHEMBL365273 | 0.91 | PLA2G4A (0.45) | ATMPLA2G4AL3MBTL1KDM4EMAPT | |
| SCHEMBL366034 | 0.89 | ATM (0.41) | ATMPLA2G4AL3MBTL1KDM4EMAPT | |
| SCHEMBL366077 | 0.87 | ATM (0.45) | ATML3MBTL1KDM4EMAPTMEN1 | |
| SCHEMBL367766 | 0.83 | L3MBTL1 (0.43) | PLA2G4AL3MBTL1MAPTKMT2ANPSR1 | |
| SCHEMBL365021 | 0.82 | SMN1; SMN2 (0.42) | ATMPLA2G4AL3MBTL1MAPTKMT2A | |
| SCHEMBL366020 | 0.81 | STS (0.41) | ATML3MBTL1KDM4EMAPTMEN1 | |
| SCHEMBL366821 | 0.81 | AGTR1 (0.41) | L3MBTL1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL367734 | 0.80 | ATM (0.40) | ATML3MBTL1KDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |