Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365176 | 0.89 | ATM (0.45) | ATML3MBTL1KDM4EMAPTPLA2G4A | |
| SCHEMBL366559 | 0.88 | ATM (0.47) | ATML3MBTL1KDM4EMAPTPLA2G4A | |
| SCHEMBL367750 | 0.86 | ATM (0.43) | ATML3MBTL1KDM4EMAPTPLA2G4A | |
| SCHEMBL366790 | 0.84 | EGFR (0.41) | KDM4EMEN1KMT2AEGFRSRC | |
| SCHEMBL367734 | 0.82 | ATM (0.40) | ATML3MBTL1KDM4EMAPTMEN1 | |
| SCHEMBL366077 | 0.82 | ATM (0.45) | ATML3MBTL1KDM4EMAPTMEN1 | |
| SCHEMBL365273 | 0.81 | PLA2G4A (0.45) | ATML3MBTL1KDM4EMAPTPLA2G4A | |
| SCHEMBL367766 | 0.78 | L3MBTL1 (0.43) | L3MBTL1MAPTPLA2G4AKMT2AEGFR | |
| SCHEMBL365021 | 0.77 | SMN1; SMN2 (0.42) | ATML3MBTL1MAPTPLA2G4AKMT2A | |
| SCHEMBL367205 | 0.76 | EGFR (0.45) | KDM4EMEN1KMT2AEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |