Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | AKT2 | P31751 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | TPMT | P51580 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367766 | 0.93 | L3MBTL1 (0.43) | L3MBTL1MAPTKMT2APLA2G4AEGFR | |
| SCHEMBL365176 | 0.91 | ATM (0.45) | ATML3MBTL1KDM4EMAPTKMT2A | |
| SCHEMBL365273 | 0.90 | PLA2G4A (0.45) | ATML3MBTL1KDM4EMAPTKMT2A | |
| SCHEMBL366559 | 0.90 | ATM (0.47) | ATML3MBTL1KDM4EMAPTKMT2A | |
| SCHEMBL365021 | 0.86 | SMN1; SMN2 (0.42) | ATML3MBTL1MAPTKMT2APLA2G4A | |
| SCHEMBL366034 | 0.86 | ATM (0.41) | ATML3MBTL1KDM4EMAPTKMT2A | |
| SCHEMBL366077 | 0.84 | ATM (0.45) | ATML3MBTL1KDM4EMAPTKMT2A | |
| SCHEMBL367256 | 0.82 | EGFR (0.40) | L3MBTL1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL366020 | 0.80 | STS (0.41) | ATML3MBTL1KDM4EMAPTKMT2A | |
| SCHEMBL365192 | 0.80 | EGFR (0.41) | ATML3MBTL1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |