Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 5/20 | 0.40 |
| ▸ | NCEH1 | Q6PIU2 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365490 | 0.90 | NCEH1 (0.39) | NCEH1KMT2AMEN1PKMRAB9A | |
| SCHEMBL365213 | 0.86 | PKM (0.39) | NCEH1NPSR1KMT2AMEN1PKM | |
| SCHEMBL365189 | 0.85 | ACHE (0.37) | NCEH1ALDH1A1 | |
| SCHEMBL366034 | 0.82 | ATM (0.41) | ATMKDM4EMAPTL3MBTL1NPSR1 | |
| SCHEMBL365769 | 0.82 | LTB4R (0.39) | KDM4EMAPTNPSR1KMT2AMEN1 | |
| SCHEMBL366020 | 0.81 | STS (0.41) | ATMKDM4EMAPTL3MBTL1NPSR1 | |
| SCHEMBL366851 | 0.80 | ALDH1A1 (0.38) | KDM4EMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL365593 | 0.80 | MRGPRX4 (0.39) | PKM | |
| SCHEMBL365176 | 0.80 | ATM (0.45) | ATMKDM4EMAPTL3MBTL1NPSR1 | |
| SCHEMBL366077 | 0.80 | ATM (0.45) | ATMKDM4EMAPTL3MBTL1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |