Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.37 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.37 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.34 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365212 | 0.90 | KMT2A (0.39) | RAB9AKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL367615 | 0.88 | IDO1 (0.42) | RAB9AKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL365489 | 0.87 | KMT2A (0.36) | RAB9AKMT2AALDH1A1MEN1PKM | |
| SCHEMBL367282 | 0.81 | KMT2A (0.47) | RAB9AKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL365406 | 0.81 | STS (0.39) | KMT2AALDH1A1MEN1KDM4EAPAF1 | |
| SCHEMBL364537 | 0.80 | BAZ2B (0.38) | KMT2AALDH1A1MEN1KDM4EAPAF1 | |
| SCHEMBL366611 | 0.80 | ACHE (0.38) | KMT2AALDH1A1MEN1KDM4EAPAF1 | |
| SCHEMBL365836 | 0.80 | MAPT (0.38) | RAB9AKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL366480 | 0.79 | ACHE (0.39) | RAB9AKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL365263 | 0.78 | EPHX1 (0.47) | RAB9AKMT2AMEN1KDM4EMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |