Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.35 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 4/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365255 | 0.90 | RAB9A (0.37) | KMT2AALDH1A1PKMRAB9ALMNA | |
| SCHEMBL367615 | 0.89 | IDO1 (0.42) | KMT2AALDH1A1PKMRAB9ALMNA | |
| SCHEMBL367733 | 0.86 | KMT2A (0.38) | KMT2AALDH1A1PKMRAB9ALMNA | |
| SCHEMBL366827 | 0.81 | KMT2A (0.45) | KMT2AALDH1A1PKMRAB9ALMNA | |
| SCHEMBL365188 | 0.80 | CYP11B1 (0.39) | KMT2AALDH1A1PKMLMNAACHE | |
| SCHEMBL366115 | 0.80 | CA1 (0.41) | KMT2AALDH1A1IDO1MEN1KDM4E | |
| SCHEMBL366789 | 0.80 | IDO1 (0.38) | KMT2AALDH1A1IDO1MEN1KDM4E | |
| SCHEMBL365768 | 0.80 | ALOX5 (0.38) | KMT2AALDH1A1PKMRAB9ALMNA | |
| SCHEMBL365592 | 0.78 | MRGPRX4 (0.39) | KMT2AALDH1A1PKMRAB9ALMNA | |
| SCHEMBL367408 | 0.77 | EPHX1 (0.51) | KMT2ARAB9AMAOBMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |