Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.42 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.38 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.38 |
| ▸ | NR2E3 | Q9Y5X4 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365212 | 0.89 | KMT2A (0.39) | IDO1NCEH1MAPTKMT2AMEN1 | |
| SCHEMBL365255 | 0.88 | RAB9A (0.37) | NCEH1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL367733 | 0.78 | KMT2A (0.38) | IDO1NCEH1MAPTKMT2AMEN1 | |
| SCHEMBL365489 | 0.77 | KMT2A (0.36) | NCEH1KMT2AMEN1ALDH1A1PKM | |
| SCHEMBL367616 | 0.73 | NCEH1 (0.46) | NCEH1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL364801 | 0.72 | ALDH1A1 (0.64) | IDO1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL366827 | 0.72 | KMT2A (0.45) | NCEH1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL367282 | 0.71 | KMT2A (0.47) | NCEH1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL365188 | 0.70 | CYP11B1 (0.39) | KMT2AALDH1A1PKMLMNA | |
| SCHEMBL365249 | 0.70 | MAPT (0.45) | IDO1MAPTKMT2AMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |