Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 3/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.37 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.36 |
| ▸ | OXTR | P30559 | 1/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3652805 | 0.87 | KDM4E (0.41) | AVPR2 | |
| Trifluoroacetic Acid SCHEMBL3657521 | 0.85 | MEN1 (0.42) | — | |
| SCHEMBL3656273 | 0.85 | HRH3 (0.44) | BCL9CTNNB1AVPR2OXTRAVPR1A | |
| Trifluoroacetic Acid SCHEMBL3654963 | 0.82 | — | — | |
| Trifluoroacetic Acid SCHEMBL3654346 | 0.82 | JAK3 (0.34) | — | |
| Trifluoroacetic Acid SCHEMBL3659571 | 0.81 | RAB9A (0.45) | — | |
| Trifluoroacetic Acid SCHEMBL3657516 | 0.81 | CA12 (0.44) | — | |
| Trifluoroacetic Acid SCHEMBL3653624 | 0.80 | KDM4E (0.40) | — | |
| Trifluoroacetic Acid SCHEMBL3652245 | 0.80 | NPC1 (0.39) | BCL9CTNNB1 | |
| Trifluoroacetic Acid SCHEMBL3653109 | 0.80 | RAB9A (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2212282-A1 | SUBSTITUTED N-PHENYL-BIPYRROLIDINE CARBOXAMIDES AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2010-08-04 | — | — | EP | disclosed |
| WO-2009052065-A1 | SUBSTITUTED N-PHENYL-BIPYRROLIDINE CARBOXAMIDES AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2009-04-23 | — | — | WO | disclosed |