SCHEMBL365525

SCHEMBL365525

Nc1ccccc1OBO

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.50
ADRA2B P18089 1/20 0.50
PTGS1 P23219 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
CYP1A2 P05177 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
KDM4E B2RXH2 3/20 0.43
MAPT P10636 1/20 0.43
CRHBP P24387 1/20 0.43
CRHR2 Q13324 1/20 0.43
APP P05067 1/20 0.41
ALOX15 P16050 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
CYP3A4 P08684 1/20 0.41
CASP1 P29466 1/20 0.41
CASP7 P55210 1/20 0.41
LMNA P02545 1/20 0.40
RECQL P46063 1/20 0.40
GAA P10253 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL2308329 0.92 ALDH1A1 (0.44) ALDH1A1ADRA2BPTGS1TDP1CYP1A2
SCHEMBL202963 0.80 ALDH1A1 (0.54) ALDH1A1ADRA2BPTGS1TDP1CYP1A2
Hydrochloric Acid SCHEMBL1234308 0.78 ALDH1A1 (0.52) ALDH1A1ADRA2BPTGS1TDP1CYP1A2
SCHEMBL410485 0.73 GAA (0.54) ALDH1A1TDP1KDM4EMAPTAPP
SCHEMBL8846148 0.72
SCHEMBL14925378 0.71 MEN1 (0.43) ALDH1A1TDP1MAPTSMN1; SMN2LMNA
SCHEMBL1638392 0.71 CA1 (0.62) ALDH1A1ADRA2BPTGS1TDP1CYP1A2
SCHEMBL9132 0.71 KDM4E (0.46) ALDH1A1TDP1CYP1A2KDM4EALOX15
SCHEMBL10035451 0.71 L3MBTL1 (0.42) ALDH1A1TDP1CYP1A2CYP2C9CYP2C19
SCHEMBL17563713 0.71 FABP7 (0.35) MAPTAPPLMNAGAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 270 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12379383-B2 Proteoform specific process validation Novilytic, LLC (US) 2025-08-05 US claimed
EP-4421168-A2 LARGE-SCALE PRODUCTION OF SOLUBLE HYALURONIDASE Halozyme, Inc. (US) 2024-08-28 EP claimed
EP-4269578-B1 SOLUBLE HYALURONIDASE COMPOSITION HALOZYME INC (US) 2024-06-05 EP claimed
EP-4269578-A1 LARGE-SCALE PRODUCTION OF SOLUBLE HYALURONIDASE Halozyme, Inc. (US) 2023-11-01 EP claimed
EP-4204158-A1 PROTEOFORM SPECIFIC PROCESS VALIDATION Novilytic, LLC (US) 2023-07-05 EP claimed
US-20220137063-A1 Proteoform Specific Process Validation TENAX BIOANALYTICS, LLC 2022-05-05 US claimed
WO-2022060947-A1 PROTEOFORM SPECIFIC PROCESS VALIDATION Novilytic, LLC (US) 2022-03-24 WO claimed
EP-2268805-B1 LARGE-SCALE PRODUCTION OF SOLUBLE HYALURONIDASE HALOZYME INC (US) 2015-05-06 EP claimed
US-8557304-B2 Method of obtaining secondary plant constituents SARTORIUS STEDIM BIOTECH GMBH (DE) 2013-10-15 US claimed
US-8187855-B2 Large-scale production of soluble hyaluronidase HALOZYME, INC. (US) 2012-05-29 US claimed
US-20120077994-A1 METHOD OF OBTAINING SECONDARY PLANT CONSTITUENTS SARTORIUS STEDIM BIOTECH GMBH (DE) 2012-03-29 US claimed
US-20110053247-A1 LARGE-SCALE PRODUCTION OF SOLUBLE HYALURONIDASE HALOZYME, INC. 2011-03-03 US claimed
EP-2268805-A1 LARGE-SCALE PRODUCTION OF SOLUBLE HYALURONIDASE Halozyme, Inc. (US) 2011-01-05 EP claimed
WO-2009111066-A1 LARGE-SCALE PRODUCTION OF SOLUBLE HYALURONIDASE HALOZYME, INC. (US) 2009-09-11 WO claimed
US-20070141678-A1 Processes for purifying oligosaccharides THE PROCTER & GAMBLE COMPANY 2007-06-21 US claimed
EP-4746986-A1 RADIAL FLOW SEPARATION DEVICE Astrea UK Services Limited (GB) 2026-05-27 EP disclosed
US-12600959-B2 PH20 polypeptide variants, formulations and uses thereof HALOZYME, INC. (US) 2026-04-14 US disclosed
EP-0487621-A4 IMMUNOASSAY OF GLYCOSYLATED PROTEINS EMPLOYING ANTIBODY DIRECTED TO REDUCTIVELY GLYCOSYLATED N-TERMINAL AMINO ACIDS 1992-06-24 EP disclosed
EP-0487621-A1 IMMUNOASSAY OF GLYCOSYLATED PROTEINS EMPLOYING ANTIBODY DIRECTED TO REDUCTIVELY GLYCOSYLATED N-TERMINAL AMINO ACIDS. UNIV NORTHWESTERN (US) 1992-06-03 EP disclosed
WO-1991002978-A1 IMMUNOASSAY OF GLYCOSYLATED PROTEINS EMPLOYING ANTIBODY DIRECTED TO REDUCTIVELY GLYCOSYLATED N-TERMINAL AMINO ACIDS NORTHWESTERN UNIVERSITY (US) 1991-03-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12600959-B2 PH20 polypeptide variants, formulations and uses thereof PREP, HM13, MMP20 ALDH1A1 1859/4885ADRA2B 4073/4885PTGS1 3779/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.