SCHEMBL10035451

SCHEMBL10035451

OBOc1ccccc1F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
PARP10 Q53GL7 1/20 0.39
CXCL8 P10145 1/20 0.39
HPGD P15428 1/20 0.39
KDM4E B2RXH2 3/20 0.38
MRGPRX4 Q96LA9 1/20 0.38
ALDH1A1 P00352 2/20 0.37
PPARG P37231 1/20 0.37
PPARA Q07869 1/20 0.37
GAA P10253 1/20 0.37
LMNA P02545 1/20 0.37
FKBP1A P62942 1/20 0.37
CYP1A2 P05177 2/20 0.36
CYP2D6 P10635 2/20 0.36
CYP2C9 P11712 2/20 0.36
CYP2C19 P33261 2/20 0.36
RECQL P46063 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11940797 0.82 SLC6A2 (0.43) L3MBTL1TDP1MRGPRX4
SCHEMBL31317053 0.82 SLC6A2 (0.43) L3MBTL1TDP1MRGPRX4
SCHEMBL290116 0.80 L3MBTL1 (0.41) L3MBTL1TDP1MEN1KMT2APARP10
SCHEMBL26210633 0.79 KMT2A (0.35) L3MBTL1TDP1MEN1KMT2AALDH1A1
SCHEMBL12157430 0.77 TRPA1 (0.39) ALDH1A1
SCHEMBL14884524 0.77 CA3 (0.43) ALDH1A1
SCHEMBL22470 0.74 L3MBTL1 (0.55) L3MBTL1TDP1KMT2AHPGDKDM4E
SCHEMBL15908020 0.74 GPR84 (0.40) L3MBTL1MEN1KMT2AKDM4EALDH1A1
SCHEMBL410485 0.73 GAA (0.54) L3MBTL1TDP1KMT2AHPGDKDM4E
SCHEMBL28288808 0.73 L3MBTL1 (0.36) L3MBTL1TDP1MEN1KMT2APARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240208991-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD (KR) 2024-06-27 US disclosed
US-20240018108-A1 METHODS AND COMPOSITIONS FOR INHIBITION OF DIHYDROOROTATE DEHYDROGENASE OHIO STATE INNOVATION FOUNDATION (US) 2024-01-18 US disclosed
US-11834459-B2 Host materials for electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2023-12-05 US disclosed
US-11766436-B2 KRAS G12C inhibitors and methods of using the same AMGEN INC. (US) 2023-09-26 US disclosed
US-20230159508-A1 INHIBITORS OF RECEPTOR INTERACTING PROTEIN KINASE I FOR THE TREATMENT OF DISEASE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2023-05-25 US disclosed
US-10026907-B2 Material for organic electroluminescence device and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2018-07-17 US disclosed
US-10020454-B2 Material for organic electroluminescence device and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2018-07-10 US disclosed
US-9978952-B2 Fused heterocyclic aromatic derivative, organic electroluminescence element material, and organic electroluminescence element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-05-22 US disclosed
US-9944629-B2 Material for organic electroluminescent element, organic electroluminescent element, illumination device, and display device Konica Minolta, Inc. (JP) 2018-04-17 US disclosed
US-20180083205-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2018-03-22 US disclosed
US-8278460-B2 Substituted benzimidazoles CONCERT PHARMACEUTICALS, INC. (US) 2012-10-02 US disclosed
US-8237002-B2 Method for producing unsaturated organic compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-08-07 US disclosed
US-20120165550-A1 Organoboron Compound and Method for Manufacturing the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-06-28 US disclosed
US-20120165556-A1 Benzo[b]Naphtho[1,2-d]Furan Compound as Light-Emitting Element Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-06-28 US disclosed
US-20120104943-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-05-03 US disclosed
US-20110253995-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2011-10-20 US disclosed
US-20110172280-A1 Substituted Benzimidazoles CONCERT PHARMACEUTICALS, INC. (US) 2011-07-14 US disclosed
US-20110046380-A1 METHOD FOR PRODUCING UNSATURATED ORGANIC COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-02-24 US disclosed
US-20100204265-A1 Certain Nitrogen Containing Bicyclic Chemical Entities for Treating Viral Infections GENELABS TECHNOLOGIES, INC. 2010-08-12 US disclosed
US-20070027150-A1 2-Amino-quinazolin-5-ones NOVARTIS VACCINES AND DIAGNOSTICS, INC. 2007-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (16 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240208991-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME CRY1, CCNL2, UBE2L3 L3MBTL1 265/4885TDP1 4600/4885MEN1 1189/4885
US-20120165550-A1 Organoboron Compound and Method for Manufacturing the Same CYP2B6, CBR3, CBR1 L3MBTL1 2201/4885TDP1 4009/4885MEN1 1969/4885
US-20230159508-A1 INHIBITORS OF RECEPTOR INTERACTING PROTEIN KINASE I FOR THE TREATMENT OF DISEASE RIPK1, RIPK2, RIPK4 L3MBTL1 2811/4885TDP1 956/4885MEN1 4212/4885
US-20100204265-A1 Certain Nitrogen Containing Bicyclic Chemical Entities for Treating Viral Infections OAT, HAVCR2, CPS1 L3MBTL1 3542/4885TDP1 3518/4885MEN1 4257/4885
US-20110253995-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME PPOX, EPCAM, STOM L3MBTL1 582/4885TDP1 3957/4885MEN1 2874/4885
US-20180083205-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME EPCAM, ILK, PPOX L3MBTL1 604/4885TDP1 3972/4885MEN1 2559/4885
US-20240018108-A1 METHODS AND COMPOSITIONS FOR INHIBITION OF DIHYDROOROTATE DEHYDROGENASE DHODH, DLD, FAH L3MBTL1 1473/4885TDP1 659/4885MEN1 1912/4885
US-10020454-B2 Material for organic electroluminescence device and organic electroluminescence device using the same PPOX, EPCAM, STOM L3MBTL1 582/4885TDP1 3957/4885MEN1 2874/4885
US-20110046380-A1 METHOD FOR PRODUCING UNSATURATED ORGANIC COMPOUND NIT2, NOS1, CHRM1 L3MBTL1 719/4885TDP1 2140/4885MEN1 65/4885
US-11834459-B2 Host materials for electroluminescent devices RPS4X, MLX, RPS4Y1 L3MBTL1 2433/4885TDP1 4472/4885MEN1 3975/4885
US-20120165556-A1 Benzo[b]Naphtho[1,2-d]Furan Compound as Light-Emitting Element Material CYP1B1, CTNND1, CTNNB1 L3MBTL1 2056/4885TDP1 2470/4885MEN1 1235/4885
US-20120104943-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME EPCAM, ILK, PPOX L3MBTL1 629/4885TDP1 3997/4885MEN1 2534/4885
US-20070027150-A1 2-Amino-quinazolin-5-ones TK1, TK2, SLC1A5 L3MBTL1 2559/4885TDP1 150/4885MEN1 754/4885
US-20110172280-A1 Substituted Benzimidazoles GABRA5, GABRB1, GABRA4 L3MBTL1 4277/4885TDP1 3396/4885MEN1 3707/4885
US-10026907-B2 Material for organic electroluminescence device and organic electroluminescence device using the same EPCAM, ILK, PPOX L3MBTL1 629/4885TDP1 3997/4885MEN1 2534/4885
US-11766436-B2 KRAS G12C inhibitors and methods of using the same KRAS, NRAS, HRAS L3MBTL1 3825/4885TDP1 3096/4885MEN1 296/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.